{"owner": "ArrayExpress Uploader", "ownerprofile_id": "arrayexpress_sid", "species": "human", "factors": [{"GSM1165979": {"STIMULATED WITH": "PMA and ionomycin for 9hrs"}}, {"GSM1165978": {"STIMULATED WITH": "none (unstimulated)"}}, {"GSM1165979": {"STIMULATED WITH": "PMA and ionomycin for 9hrs"}}, {"GSM1165978": {"STIMULATED WITH": "none (unstimulated)"}}], "id": 2390, "pop_total": 0, "platform": 4, "summary_wrapped": "Human T-cell leukemia virus type 1 (HTLV-1) encodes HTLV-1 bZIP factor (HBZ), which is thought to be crucial for neoplastic and...", "geo_gse_id": "E-GEOD-48029", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 4, "tags": ["cell", "genome", "leukemia", "t-cell leukemia"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "expression-data-of-jurkat-cells-stably-expressing", "geo_id_plat": "E-GEOD-48029_A-AFFY-44", "name": "Expression data of Jurkat cells stably expressing HBZ with or without stimulation", "created": "Jul.12, 2014", "summary": "Human T-cell leukemia virus type 1 (HTLV-1) encodes HTLV-1 bZIP factor (HBZ), which is thought to be crucial for neoplastic and inflammatory diseases caused by HTLV-1. So, we analyzed the transcriptional profile of HBZ expressing cells and how HBZ affect the expression of apoptosis-related genes. We used microarrays to detail the effect of HTLV-1 bZIP factor (HBZ), which is encoded in the minus strand of HTLV-1 genome on gene expression. Especially how HBZ affect the expression of apoptosis-related genes. Jurkat cells stably expressing HBZ were stimulated with or without PMA and ionomycin for 9hours. Then  RNA extraction and hybridization on Affymetrix microarrays were performed.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-48029", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-48029/samples/"}