Dataset: Impact of resistance exercise on human skeletal muscle gene expression - ageing

The aim of this work was to produce a reproducible molecular signature of human muscle responses to resistance training and examine how...

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The aim of this work was to produce a reproducible molecular signature of human muscle responses to resistance training and examine how such a profile relates to new and established exercise adaptation gene networks. Subjects were recruited from an age range of 18 to 75 y. Before beginning the study all subjects were screened using a medical questionnaire, physical examination and resting ECG with exclusions for overt muscle wasting (>2 SD below age norms)[85], metabolic, respiratory/cardiovascular disorders or other major contraindications to a healthy status. All subjects had normal blood chemistry and were normotensive (BP <140/90). All subjects performed routine activities of daily living and recreation but did not participate in moderate to high intensity aerobic exercise and none had participated in RET in the last 24 months. Body composition was measured at screening and following RET by dual energy X-ray absorptiometry (DEXA) (Lunar Prodigy II, GE Medical Systems). Subject positioning on the DEXA bed was optimized to allow the region of interest (ROI) body compartments to be analyzed separately. The upper leg ROI was selected as the area inferior to the lowest visible point of the coccyx to the mid-point of the patella. The dataset comprises 44 pre-exercise and 44 post-exercise samples. In addition there is a baseline sample NB021_pre-training (D13_NB021F). Therefore there are 89 samples in total. (Note: Singleton baseline sample NB021_pre-training was normalized only using all baseline samples.) Derby dataset.

Species:: human
Samples:: 89
Source:: E-GEOD-47881
PubMed:: 23555298
Updated:: Dec.12, 2014
Registered:: Jul.12, 2014

Factors: (via ArrayExpress)

Sample	AGE	PATIENTID	TIME
GSM1161859	49	TW003	post-training
GSM1161858	49	TW003	pre-training
GSM1161857	28	SJ079	post-training
GSM1161856	28	SJ079	pre-training
GSM1161855	69	SH041	post-training
GSM1161854	69	SH041	pre-training
GSM1161853	47	SF065	post-training
GSM1161852	47	SF065	pre-training
GSM116185	45	SB063	post-training
GSM1161850	45	SB063	pre-training
GSM1161849	72	RP012	post-training
GSM1161848	72	RP012	pre-training
GSM1161847	47	RN039	post-training
GSM1161846	47	RN039	pre-training
GSM1161845	73	RG093	post-training
GSM1161844	73	RG093	pre-training
GSM1161843	67	RB020	post-training
GSM1161842	67	RB020	pre-training
GSM116184	75	PW031	post-training
GSM1161840	75	PW031	pre-training
GSM1161839	49	PK029	post-training
GSM1161838	49	PK029	pre-training
GSM1161837	45	PG069	post-training
GSM1161836	45	PG069	pre-training
GSM1161835	66	PC035	post-training
GSM1161834	66	PC035	pre-training
GSM1161833	28	NB021	pre-training
GSM1161832	26	MT008	post-training
GSM116183	26	MT008	pre-training
GSM1161830	69	MJ022	post-training
GSM1161829	69	MJ022	pre-training
GSM1161828	52	MH061	post-training
GSM1161827	52	MH061	pre-training
GSM1161826	28	MH054	post-training
GSM1161825	28	MH054	pre-training
GSM1161824	71	LH091	pre-training
GSM1161823	71	LH091	post-training
GSM1161822	49	KA070	post-training
GSM116182	49	KA070	pre-training
GSM1161820	69	JW087	post-training
GSM1161819	69	JW087	pre-training
GSM1161818	74	JOH099	post-training
GSM1161817	74	JOH099	pre-training
GSM1161816	47	JH074	post-training
GSM1161815	47	JH074	pre-training
GSM1161814	20	JG040	post-training
GSM1161813	20	JG040	pre-training
GSM1161812	64	JC064	post-training
GSM11618	64	JC064	pre-training
GSM1161810	27	JC047	post-training
GSM1161809	27	JC047	pre-training
GSM1161808	55	JB044	post-training
GSM1161807	55	JB044	pre-training
GSM1161806	28	JB038	post-training
GSM1161805	28	JB038	pre-training
GSM1161804	67	JA071	post-training
GSM1161803	67	JA071	pre-training
GSM1161802	51	IM023	post-training
GSM116180	51	IM023	pre-training
GSM1161800	72	HA094	post-training
GSM1161799	72	HA094	pre-training
GSM1161798	65	GS075	post-training
GSM1161797	65	GS075	pre-training
GSM1161796	71	GJ095	post-training
GSM1161795	71	GJ095	pre-training
GSM1161794	46	EH014	post-training
GSM1161793	46	EH014	pre-training
GSM1161792	74	ED049	post-training
GSM116179	74	ED049	pre-training
GSM1161790	54	DW097	post-training
GSM1161789	54	DW097	pre-training
GSM1161788	51	DT067	post-training
GSM1161787	51	DT067	pre-training
GSM1161786	54	CS066	post-training
GSM1161785	54	CS066	pre-training
GSM1161784	26	CR053	post-training
GSM1161783	26	CR053	pre-training
GSM1161782	48	CP068	post-training
GSM116178	48	CP068	pre-training
GSM1161780	45	CL046	post-training
GSM1161779	45	CL046	pre-training
GSM1161778	55	CF093	post-training
GSM1161777	55	CF093	pre-training
GSM1161776	21	BH073	post-training
GSM1161775	21	BH073	pre-training
GSM1161774	46	AS060	post-training
GSM1161773	46	AS060	pre-training
GSM1161772	25	AC033	post-training
GSM116177	25	AC033	pre-training