{"platform": 4, "owner": "ArrayExpress Uploader", "ownerprofile_id": "arrayexpress_sid", "species": "human", "factors": [{"GSM1161366": {"TREATMENT": "MBD2 transfection"}}, {"GSM1161366": {"TREATMENT": "MBD2 transfection"}}, {"GSM1161366": {"TREATMENT": "MBD2 transfection"}}, {"GSM1161363": {"TREATMENT": "control"}}, {"GSM1161363": {"TREATMENT": "control"}}, {"GSM1161363": {"TREATMENT": "control"}}], "id": 2391, "pop_total": 0, "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-47873", "summary_wrapped": "Methylated DNA binding protein 2 (MBD2) has been shown to bind specific methylated promoters and suppress transcription. Here we...", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 6, "tags": ["protein"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "gene-expression-profiles-mcf-10a-cells-overexpress", "geo_id_plat": "E-GEOD-47873_A-AFFY-44", "name": "Gene expression profiles MCF-10A cells overexpressing MBD2", "created": "Jul.12, 2014", "summary": "Methylated DNA binding protein 2 (MBD2) has been shown to bind specific methylated promoters and suppress transcription. Here we systematically investigate MBD2 suppression by overexpressing MBD2 in MCF-10A cells and generating gene expression profiles of overexpressing cells and normal MCF-10A cells. MCF-10A cells were infected with MBD2 lentivirus in order to increase MBD2 expression. Total RNA was extracted from both infected and non-infected cells and hybridized to Affymetrix gene expression microarrays. Three technical replicates were hybridized for infected and non-infected cells.", "geo_gse_id": "E-GEOD-47873", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-47873/samples/"}