{"owner": "ArrayExpress Uploader", "ownerprofile_id": "arrayexpress_sid", "species": "human", "factors": [{"GSM1155707": {"TREATMENT": "transduced with p63+KLF4 expressing retrovirus and treated with high calcium"}}, {"GSM1155707": {"TREATMENT": "transduced with p63+KLF4 expressing retrovirus and treated with high calcium"}}, {"GSM1155705": {"TREATMENT": "transduced with p63+KLF4 expressing retrovirus and treated with low calcium"}}, {"GSM1155705": {"TREATMENT": "transduced with p63+KLF4 expressing retrovirus and treated with low calcium"}}, {"GSM1155703": {"TREATMENT": "transduced with p63+KLF4 expressing retrovirus"}}, {"GSM1155703": {"TREATMENT": "transduced with p63+KLF4 expressing retrovirus"}}, {"GSM115570": {"TREATMENT": "transduced with LacZ expressing retrovirus"}}, {"GSM115570": {"TREATMENT": "transduced with LacZ expressing retrovirus"}}], "id": 2237, "pop_total": 0, "platform": 4, "summary_wrapped": "To determine if fibroblasts could be reprogrammed to a keratinocyte phenotype p63+KLF4 or LacZ expressing retroviruses were transduced...", "geo_gse_id": "E-GEOD-47746", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 8, "tags": [], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "gene-expression-data-of-fibroblasts-transduced-wit", "geo_id_plat": "E-GEOD-47746_A-AFFY-44", "name": "Gene expression data of fibroblasts transduced with LacZ or p63+KLF4.", "created": "Jul.11, 2014", "summary": "To determine if fibroblasts could be reprogrammed to a keratinocyte phenotype p63+KLF4 or LacZ expressing retroviruses were transduced into primary human neonatal fibroblasts. Global gene expression profiling using U133 plus 2.0 arrays were used to deteremine the extent of reprogramming to a keratinocyte phenoypte upon transduction with p63+KLF4. Fibroblasts transduced with p63+KLF4 were also treated +/- high calcium to determine if treatment with calcium could induce differentiation of these cells. Microarray analysis was also performed on cells treated +/- calcium. For gene expression profiling, cultured human fibroblasts were infected with LacZ or p63+KLF4 expressing retroviruses. p63+KLF4 cells were also treated +/- calcium.  Microarray analysis using Affymetrix HG-U133 2.0 plus arrays was performed on duplicate samples.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-47746", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-47746/samples/"}