{"owner": "ArrayExpress Uploader", "pop_total": 0, "id": 7303, "factors": [{"GSM1143763": {"GENOTYPE": "Gata6-KO"}}, {"GSM1143763": {"GENOTYPE": "Gata6-KO"}}, {"GSM1143763": {"GENOTYPE": "Gata6-KO"}}, {"GSM1143766": {"GENOTYPE": "Gata6-WT"}}, {"GSM1143766": {"GENOTYPE": "Gata6-WT"}}, {"GSM1143766": {"GENOTYPE": "Gata6-WT"}}], "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "Tissue resident macrophages are notoriously heterogeneous, exhibiting discrete phenotypes as a consequence of tissue- and micro-...", "pubmed_id": 24762537, "geo_gse_id": "E-GEOD-47049", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 6, "tags": ["macrophage"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "expression-data-from-wild-type-and-gata6-deficient", "geo_id_plat": "E-GEOD-47049_A-AFFY-45", "name": "Expression data from wild type and Gata6-deficient tissue resident peritoneal macrophages", "created": "Nov.12, 2014", "summary": "Tissue resident macrophages are notoriously heterogeneous, exhibiting discrete phenotypes as a consequence of tissue- and micro-anatomical niche-specific functions, but the molecular basis for this is not understood. We resolved a restricted transcriptional profile for the self-renewing population of peritoneal resident macrophages, which is expressed during homeostasis and inflammation and distinct from other M\u00d8. Prominent within this profile was the expression of Gata6. This study represents a characterisation of the role of Gata6 in peritoneal resident macrophage phenotype. We used microarrays to determine the patterns of gene expression in peritoneal resident M\u00d8 in the absence of GATA-6 against wild type. Conditional 'floxed' Gata6 deficient sex-matched mice between 7 weeks old were compared against wild type", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-47049", "species": "mouse", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-47049/samples/"}