{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSM1143043": {"TREATMENT": "control", "BODY WEIGHT": "regular weight"}}, {"GSM1143043": {"TREATMENT": "control", "BODY WEIGHT": "regular weight"}}, {"GSM1143043": {"TREATMENT": "control", "BODY WEIGHT": "regular weight"}}, {"GSM1143043": {"TREATMENT": "control", "BODY WEIGHT": "regular weight"}}, {"GSM1143043": {"TREATMENT": "control", "BODY WEIGHT": "regular weight"}}, {"GSM1143043": {"TREATMENT": "control", "BODY WEIGHT": "regular weight"}}, {"GSM1143043": {"TREATMENT": "control", "BODY WEIGHT": "regular weight"}}, {"GSM1143043": {"TREATMENT": "control", "BODY WEIGHT": "regular weight"}}, {"GSM114305": {"TREATMENT": "control", "BODY WEIGHT": "Obese"}}, {"GSM114305": {"TREATMENT": "control", "BODY WEIGHT": "Obese"}}, {"GSM114305": {"TREATMENT": "control", "BODY WEIGHT": "Obese"}}, {"GSM114305": {"TREATMENT": "control", "BODY WEIGHT": "Obese"}}, {"GSM114305": {"TREATMENT": "control", "BODY WEIGHT": "Obese"}}, {"GSM114305": {"TREATMENT": "control", "BODY WEIGHT": "Obese"}}, {"GSM114305": {"TREATMENT": "control", "BODY WEIGHT": "Obese"}}, {"GSM114305": {"TREATMENT": "control", "BODY WEIGHT": "Obese"}}, {"GSM1143059": {"TREATMENT": "Mainstream smoke (MS)", "BODY WEIGHT": "regular weight"}}, {"GSM1143059": {"TREATMENT": "Mainstream smoke (MS)", "BODY WEIGHT": "regular weight"}}, {"GSM1143059": {"TREATMENT": "Mainstream smoke (MS)", "BODY WEIGHT": "regular weight"}}, {"GSM1143059": {"TREATMENT": "Mainstream smoke (MS)", "BODY WEIGHT": "regular weight"}}, {"GSM1143059": {"TREATMENT": "Mainstream smoke (MS)", "BODY WEIGHT": "regular weight"}}, {"GSM1143059": {"TREATMENT": "Mainstream smoke (MS)", "BODY WEIGHT": "regular weight"}}, {"GSM1143059": {"TREATMENT": "Mainstream smoke (MS)", "BODY WEIGHT": "regular weight"}}, {"GSM1143059": {"TREATMENT": "Mainstream smoke (MS)", "BODY WEIGHT": "regular weight"}}, {"GSM1143067": {"TREATMENT": "Mainstream smoke (MS)", "BODY WEIGHT": "Obese"}}, {"GSM1143067": {"TREATMENT": "Mainstream smoke (MS)", "BODY WEIGHT": "Obese"}}, {"GSM1143067": {"TREATMENT": "Mainstream smoke (MS)", "BODY WEIGHT": "Obese"}}, {"GSM1143067": {"TREATMENT": "Mainstream smoke (MS)", "BODY WEIGHT": "Obese"}}, {"GSM1143067": {"TREATMENT": "Mainstream smoke (MS)", "BODY WEIGHT": "Obese"}}, {"GSM1143067": {"TREATMENT": "Mainstream smoke (MS)", "BODY WEIGHT": "Obese"}}, {"GSM1143073": {"TREATMENT": "Sidestream smoke (SS)", "BODY WEIGHT": "regular weight"}}, {"GSM1143073": {"TREATMENT": "Sidestream smoke (SS)", "BODY WEIGHT": "regular weight"}}, {"GSM1143073": {"TREATMENT": "Sidestream smoke (SS)", "BODY WEIGHT": "regular weight"}}, {"GSM1143073": {"TREATMENT": "Sidestream smoke (SS)", "BODY WEIGHT": "regular weight"}}, {"GSM1143073": {"TREATMENT": "Sidestream smoke (SS)", "BODY WEIGHT": "regular weight"}}, {"GSM1143073": {"TREATMENT": "Sidestream smoke (SS)", "BODY WEIGHT": "regular weight"}}, {"GSM1143073": {"TREATMENT": "Sidestream smoke (SS)", "BODY WEIGHT": "regular weight"}}, {"GSM1143080": {"TREATMENT": "Sidestream smoke (SS)", "BODY WEIGHT": "Obese"}}, {"GSM1143080": {"TREATMENT": "Sidestream smoke (SS)", "BODY WEIGHT": "Obese"}}, {"GSM1143080": {"TREATMENT": "Sidestream smoke (SS)", "BODY WEIGHT": "Obese"}}, {"GSM1143080": {"TREATMENT": "Sidestream smoke (SS)", "BODY WEIGHT": "Obese"}}, {"GSM1143080": {"TREATMENT": "Sidestream smoke (SS)", "BODY WEIGHT": "Obese"}}, {"GSM1143080": {"TREATMENT": "Sidestream smoke (SS)", "BODY WEIGHT": "Obese"}}, {"GSM1143080": {"TREATMENT": "Sidestream smoke (SS)", "BODY WEIGHT": "Obese"}}, {"GSM1143080": {"TREATMENT": "Sidestream smoke (SS)", "BODY WEIGHT": "Obese"}}], "id": 8707, "ownerprofile_id": "arrayexpress_sid", "platform": 8, "summary_wrapped": "To identify biosignatures that describe these lifestyle susceptibility factors, we performed parallel exposures of regular weight (RW)...", "geo_gse_id": "E-GEOD-47022", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 45, "tags": ["hand", "heart", "nose"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "impaired-transcriptional-response-of-the-murine-he", "geo_id_plat": "E-GEOD-47022_A-AFFY-36", "name": "Impaired Transcriptional Response of the Murine Heart To Cigarette Smoke in the Setting of High Fat Diet and Obesity", "created": "Nov.24, 2014", "summary": "To identify biosignatures that describe these lifestyle susceptibility factors, we performed parallel exposures of regular weight (RW) C57BL/6 and diet-induced obese (DIO) C57BL/6 mice to cigarette smoke, either mainstream (MS) or sidestream (SS), mimicking both the smoker and environmental exposure through second-hand smoke, respectively. Transcriptional responses were measured by global microarray analysis of heart tissue. Groups (N=6-8 biological replicates) of RW and DIO C57BL/6 mice (15-weeks old at start of exposures) were exposed to either filtered air (sham controls, SC), mainstream (MS) or sidestream (SS) cigarette smoke by nose-only inhalation exposure for 5 hr/day for a total of eight exposures over two weeks as follows: 5 consecutive days of exposure, followed by 2 days with no exposure, then three days of exposure, with necropsies occurring the day following the last exposure.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-47022", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-47022/samples/"}