{"owner": "ArrayExpress Uploader", "ownerprofile_id": "arrayexpress_sid", "species": "human", "factors": [{"GSM1141025 1": {"CELL TYPE": "MDC", "SUBJECT": "HD1"}}, {"GSM1141026 1": {"CELL TYPE": "MDC", "SUBJECT": "HD11"}}, {"GSM1141027 1": {"CELL TYPE": "MDC", "SUBJECT": "HD19"}}, {"GSM1141028 1": {"CELL TYPE": "MDC", "SUBJECT": "HD5"}}, {"GSM1141029 1": {"CELL TYPE": "MDC", "SUBJECT": "HD6"}}, {"GSM1141030 1": {"CELL TYPE": "monocyte", "SUBJECT": "HD1"}}, {"GSM1141031 1": {"CELL TYPE": "monocyte", "SUBJECT": "HD5"}}, {"GSM1141032 1": {"CELL TYPE": "monocyte", "SUBJECT": "HD6"}}, {"GSM1141033 1": {"CELL TYPE": "monocyte", "SUBJECT": "HD11"}}, {"GSM1141034 1": {"CELL TYPE": "monocyte", "SUBJECT": "HD19"}}], "id": 10016, "pop_total": 0, "platform": 3, "summary_wrapped": "To directly compare the SLE monocyte transcriptional program with that of blood mDC precursors, we purified lineage HLA-DRhighCD11chigh...", "pubmed_id": 24829414, "geo_gse_id": "E-GEOD-46913", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 0, "sample_count": 10, "tags": ["monocyte"], "lastmodified": "Jan.28, 2015", "is_default": false, "geo_gds_id": "", "slug": "transcripts-differentially-expressed-in-healthy-bl", "geo_id_plat": "E-GEOD-46913_A-AFFY-33", "name": "Transcripts differentially expressed in healthy blood mDCs compared to healthy monocytes", "created": "Jan.28, 2015", "summary": "To directly compare the SLE monocyte transcriptional program with that of blood mDC precursors, we purified lineage HLA-DRhighCD11chigh mDCs and CD14+ monocytes from the blood of five healthy donors. Their gene expression profiles were then compared to those of blood SLE monocytes. An unsupervised clustering analysis of transcripts present in >20% of the samples classified healthy monocytes, SLE monocytes and healthy mDCs into three well defined groups. A supervised analysis was then performed to find genes: 1) differentially expressed in healthy mDCs compared to monocytes; 2) shared by healthy blood mDCs and SLE blood monocytes. To directly compare the SLE monocyte transcriptional program with that of blood mDC precursors, we purified lineage HLA-DRhighCD11chigh mDCs and CD14+ monocytes from the blood of five healthy donors. Their gene expression profiles were then compared to those of blood SLE monocytes. An unsupervised clustering analysis of transcripts present in >20% of the samples classified healthy monocytes, SLE monocytes and healthy mDCs into three well defined groups. A supervised analysis was then performed to find genes: 1) differentially expressed in healthy mDCs compared to monocytes; 2) shared by healthy blood mDCs and SLE blood monocytes.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-46913", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-46913/samples/"}