{"owner": "ArrayExpress Uploader", "ownerprofile_id": "arrayexpress_sid", "species": "mouse", "factors": [{"GSM1139004": {"SARCOMA/TUMOR": "pleomorphic RMS (pRMS)", "GENOTYPE": "mutant Kras and loss of both alleles of p53 in Pax7+ cells", "SARCOMA DERIVED FROM": "Pax7+ cells"}}, {"GSM1139004": {"SARCOMA/TUMOR": "pleomorphic RMS (pRMS)", "GENOTYPE": "mutant Kras and loss of both alleles of p53 in Pax7+ cells", "SARCOMA DERIVED FROM": "Pax7+ cells"}}, {"GSM1139004": {"SARCOMA/TUMOR": "pleomorphic RMS (pRMS)", "GENOTYPE": "mutant Kras and loss of both alleles of p53 in Pax7+ cells", "SARCOMA DERIVED FROM": "Pax7+ cells"}}, {"GSM1139004": {"SARCOMA/TUMOR": "pleomorphic RMS (pRMS)", "GENOTYPE": "mutant Kras and loss of both alleles of p53 in Pax7+ cells", "SARCOMA DERIVED FROM": "Pax7+ cells"}}, {"GSM1139004": {"SARCOMA/TUMOR": "pleomorphic RMS (pRMS)", "GENOTYPE": "mutant Kras and loss of both alleles of p53 in Pax7+ cells", "SARCOMA DERIVED FROM": "Pax7+ cells"}}, {"GSM1139004": {"SARCOMA/TUMOR": "pleomorphic RMS (pRMS)", "GENOTYPE": "mutant Kras and loss of both alleles of p53 in Pax7+ cells", "SARCOMA DERIVED FROM": "Pax7+ cells"}}, {"GSM1139010": {"SARCOMA/TUMOR": "embryonal RMS (eRMS)", "GENOTYPE": "mutant Kras and loss of both alleles of p53 in Pax7+ cells", "SARCOMA DERIVED FROM": "Pax7+ cells"}}, {"GSM1139010": {"SARCOMA/TUMOR": "embryonal RMS (eRMS)", "GENOTYPE": "mutant Kras and loss of both alleles of p53 in Pax7+ cells", "SARCOMA DERIVED FROM": "Pax7+ cells"}}, {"GSM1139010": {"SARCOMA/TUMOR": "embryonal RMS (eRMS)", "GENOTYPE": "mutant Kras and loss of both alleles of p53 in Pax7+ cells", "SARCOMA DERIVED FROM": "Pax7+ cells"}}, {"GSM1139010": {"SARCOMA/TUMOR": "embryonal RMS (eRMS)", "GENOTYPE": "mutant Kras and loss of both alleles of p53 in Pax7+ cells", "SARCOMA DERIVED FROM": "Pax7+ cells"}}, {"GSM1139010": {"SARCOMA/TUMOR": "embryonal RMS (eRMS)", "GENOTYPE": "mutant Kras and loss of both alleles of p53 in Pax7+ cells", "SARCOMA DERIVED FROM": "Pax7+ cells"}}, {"GSM1139010": {"SARCOMA/TUMOR": "embryonal RMS (eRMS)", "GENOTYPE": "mutant Kras and loss of both alleles of p53 in Pax7+ cells", "SARCOMA DERIVED FROM": "Pax7+ cells"}}, {"GSM1139010": {"SARCOMA/TUMOR": "embryonal RMS (eRMS)", "GENOTYPE": "mutant Kras and loss of both alleles of p53 in Pax7+ cells", "SARCOMA DERIVED FROM": "Pax7+ cells"}}, {"GSM1139017": {"SARCOMA/TUMOR": "undifferentiated pleomorphic sarcoma (UPS)", "GENOTYPE": "mutant Kras and loss of both alleles of p53 in Pax7+ cells", "SARCOMA DERIVED FROM": "Pax7+ cells"}}, {"GSM1139017": {"SARCOMA/TUMOR": "undifferentiated pleomorphic sarcoma (UPS)", "GENOTYPE": "mutant Kras and loss of both alleles of p53 in Pax7+ cells", "SARCOMA DERIVED FROM": "Pax7+ cells"}}, {"GSM1139017": {"SARCOMA/TUMOR": "undifferentiated pleomorphic sarcoma (UPS)", "GENOTYPE": "mutant Kras and loss of both alleles of p53 in Pax7+ cells", "SARCOMA DERIVED FROM": "Pax7+ cells"}}, {"GSM1139017": {"SARCOMA/TUMOR": "undifferentiated pleomorphic sarcoma (UPS)", "GENOTYPE": "mutant Kras and loss of both alleles of p53 in Pax7+ cells", "SARCOMA DERIVED FROM": "Pax7+ cells"}}, {"GSM1139017": {"SARCOMA/TUMOR": "undifferentiated pleomorphic sarcoma (UPS)", "GENOTYPE": "mutant Kras and loss of both alleles of p53 in Pax7+ cells", "SARCOMA DERIVED FROM": "Pax7+ cells"}}, {"GSM1139017": {"SARCOMA/TUMOR": "undifferentiated pleomorphic sarcoma (UPS)", "GENOTYPE": "mutant Kras and loss of both alleles of p53 in Pax7+ cells", "SARCOMA DERIVED FROM": "Pax7+ cells"}}, {"GSM1139017": {"SARCOMA/TUMOR": "undifferentiated pleomorphic sarcoma (UPS)", "GENOTYPE": "mutant Kras and loss of both alleles of p53 in Pax7+ cells", "SARCOMA DERIVED FROM": "Pax7+ cells"}}, {"GSM1139024": {"SARCOMA/TUMOR": "MyoD-derived sarcoma (MDKP)", "GENOTYPE": "mutant Kras and loss of both alleles of p53 in MyoD+ cells", "SARCOMA DERIVED FROM": "MyoD+ cells"}}, {"GSM1139024": {"SARCOMA/TUMOR": "MyoD-derived sarcoma (MDKP)", "GENOTYPE": "mutant Kras and loss of both alleles of p53 in MyoD+ cells", "SARCOMA DERIVED FROM": "MyoD+ cells"}}, {"GSM1139024": {"SARCOMA/TUMOR": "MyoD-derived sarcoma (MDKP)", "GENOTYPE": "mutant Kras and loss of both alleles of p53 in MyoD+ cells", "SARCOMA DERIVED FROM": "MyoD+ cells"}}, {"GSM1139024": {"SARCOMA/TUMOR": "MyoD-derived sarcoma (MDKP)", "GENOTYPE": "mutant Kras and loss of both alleles of p53 in MyoD+ cells", "SARCOMA DERIVED FROM": "MyoD+ cells"}}, {"GSM1139024": {"SARCOMA/TUMOR": "MyoD-derived sarcoma (MDKP)", "GENOTYPE": "mutant Kras and loss of both alleles of p53 in MyoD+ cells", "SARCOMA DERIVED FROM": "MyoD+ cells"}}, {"GSM1139024": {"SARCOMA/TUMOR": "MyoD-derived sarcoma (MDKP)", "GENOTYPE": "mutant Kras and loss of both alleles of p53 in MyoD+ cells", "SARCOMA DERIVED FROM": "MyoD+ cells"}}, {"GSM1139024": {"SARCOMA/TUMOR": "MyoD-derived sarcoma (MDKP)", "GENOTYPE": "mutant Kras and loss of both alleles of p53 in MyoD+ cells", "SARCOMA DERIVED FROM": "MyoD+ cells"}}], "id": 8706, "pop_total": 0, "platform": 8, "summary_wrapped": "The cell of origin for rhabdomyosarcoma (RMS) and undifferentiated pleomorphic sarcoma (UPS) remains to be determined.  We utilized two...", "geo_gse_id": "E-GEOD-46836", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 3, "sample_count": 27, "tags": ["cell", "liquid", "muscle", "rhabdomyosarcoma", "sarcoma"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "expression-data-from-murine-sarcomas", "geo_id_plat": "E-GEOD-46836_A-AFFY-36", "name": "Expression data from murine sarcomas", "created": "Nov.24, 2014", "summary": "The cell of origin for rhabdomyosarcoma (RMS) and undifferentiated pleomorphic sarcoma (UPS) remains to be determined.  We utilized two skeletal muscle specific inducible Cre mouse lines to transform both skeletal muscle stem cells and progenitors to determine which cells give rise to RMS and UPS. Both P7KP and MDKP derived mice were injected with systemic tamoxifen and mice were euthanized after tumor development.  Sections of resected tumor were placed in RNAlater and placed at -80 until RNA isolation.  RNA was isolated by grinding up tumor sections in liquid nitrogen and using the Qiagen RNEasy Micro kit.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-46836", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-46836/samples/"}