{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSM1129194": {"SAMPLE TYPE": "overexpressing miR-125b plus miR-99a and miR-100"}}, {"GSM1129194": {"SAMPLE TYPE": "overexpressing miR-125b plus miR-99a and miR-100"}}, {"GSM1129194": {"SAMPLE TYPE": "overexpressing miR-125b plus miR-99a and miR-100"}}, {"GSM112919": {"SAMPLE TYPE": "overexpressing miR-125b plus miR-100"}}, {"GSM112919": {"SAMPLE TYPE": "overexpressing miR-125b plus miR-100"}}, {"GSM112919": {"SAMPLE TYPE": "overexpressing miR-125b plus miR-100"}}, {"GSM1129188": {"SAMPLE TYPE": "overexpressing miR-125b plus miR-99a"}}, {"GSM1129188": {"SAMPLE TYPE": "overexpressing miR-125b plus miR-99a"}}, {"GSM1129188": {"SAMPLE TYPE": "overexpressing miR-125b plus miR-99a"}}, {"GSM1129185": {"SAMPLE TYPE": "overexpressing miR-125b plus scrambled miR-control"}}, {"GSM1129185": {"SAMPLE TYPE": "overexpressing miR-125b plus scrambled miR-control"}}], "id": 2379, "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "Combined overexpression of miR-125b with miR-99a and/or miR-100 induced VCR resistance in ETV6-RUNX1-positive leukemic cells Reh. We used...", "geo_gse_id": "E-GEOD-46362", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 11, "tags": [], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "expression-data-from-etv6-runx1-positive-reh-leuke", "geo_id_plat": "E-GEOD-46362_A-AFFY-44", "name": "Expression data from ETV6-RUNX1-positive Reh leukemic cells after overexpression of miR-125b, miR-100 and miR-99a levels in different combinations", "created": "Jul.12, 2014", "summary": "Combined overexpression of miR-125b with miR-99a and/or miR-100 induced VCR resistance in ETV6-RUNX1-positive leukemic cells Reh. We used microarrays to detail the global changes in gene expression of Reh cells upon enforced expression of miR-125 per se compared with combination of overexpression of miR-125b, miR-100 and/or miR-99a MiR-99a and/or miR-100 were transiently overexpressed in stable miR-125b-expressing and stable scrambled miR-control-expressing Reh cells. Cellular resistance to VCR was determined by MTT assay after incubating the cells with 9 ng/mL VCR for 3 days. Changes in the gene expression pattern of Reh cells induced by miRNAs overexpression were measured using Affymetrix Arrays.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-46362", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-46362/samples/"}