ArrayExpress Uploader072441None (control) for 1h2None (control) for 1h3None (control) for 1h1None (control) for 24h2None (control) for 24h3None (control) for 24h1None (control) for 6h2None (control) for 6h3None (control) for 6h1PTH(1–34) (10 nM) for 1h2PTH(1–34) (10 nM) for 1h3PTH(1–34) (10 nM) for 1h1PTH(1–34) (10 nM) for 24h2PTH(1–34) (10 nM) for 24h3PTH(1–34) (10 nM) for 24h1PTH(1–34) (10 nM) for 6h2PTH(1–34) (10 nM) for 6h3PTH(1–34) (10 nM) for 6h1PTHrP(1–141) (20 nM) for 1hr2PTHrP(1–141) (20 nM) for 1hr3PTHrP(1–141) (20 nM) for 1hr1PTHrP(1–141) (20 nM) for 24hr2PTHrP(1–141) (20 nM) for 24hr3PTHrP(1–141) (20 nM) for 24hr1PTHrP(1–141) (20 nM) for 6hr2PTHrP(1–141) (20 nM) for 6hr3PTHrP(1–141) (20 nM) for 6hrarrayexpress_sid6With the aim of identifying new pathways and genes regulated by PTH(1-34) and PTH-related protein 1-141 [PTHrP(1-141)] in osteoblasts,...18627264E-GEOD-45895/profile/8773/arrayexpressuploader227cellgenomelineproteinstromal cellDec.12, 2014Falseephrinb2-regulation-by-pth-and-pthrp-revealed-by-mE-GEOD-45895_A-AFFY-45EphrinB2 Regulation by PTH and PTHrP Revealed by Molecular Profiling in Differentiating OsteoblastsNov.12, 2014With the aim of identifying new pathways and genes regulated by PTH(1-34) and PTH-related protein 1-141 [PTHrP(1-141)] in osteoblasts, this study was carried out using a mouse marrow stromal cell line, Kusa 4b10, that acquires features of the osteoblastic phenotype in long-term culture conditions. After the appearance of functional PTH receptor 1 (PTHR1) in Kusa 4b10 cells, they were treated with either PTH(1-34) or PTHrP(1-141), and RNA was subjected to Affymetrix whole mouse genome array. Timecourse experiment on Kusa4b10 cell lines, treatment with PTH or PTHrP, collection at 1, 6 and 24 hours NOTE: This work has been published in 2008 (PMID 18627264); Since the original normalised data for this project is unavailable, the data has been re-normalised using a standard method for GEO submission in 2013. Therefore, the re-normalized data represented in this records may differ slightly from the original normalized data in the publication.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-45895mousehttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-45895/samples/