{"owner": "ArrayExpress Uploader", "pop_total": 0, "id": 7244, "factors": [{"GSM1119263": {"REPLICATE": 1, "TREATED WITH": "None (control) for 1h"}}, {"GSM1119264": {"REPLICATE": 2, "TREATED WITH": "None (control) for 1h"}}, {"GSM1119265": {"REPLICATE": 3, "TREATED WITH": "None (control) for 1h"}}, {"GSM1119266": {"REPLICATE": 1, "TREATED WITH": "None (control) for 24h"}}, {"GSM1119267": {"REPLICATE": 2, "TREATED WITH": "None (control) for 24h"}}, {"GSM1119268": {"REPLICATE": 3, "TREATED WITH": "None (control) for 24h"}}, {"GSM1119269": {"REPLICATE": 1, "TREATED WITH": "None (control) for 6h"}}, {"GSM1119270": {"REPLICATE": 2, "TREATED WITH": "None (control) for 6h"}}, {"GSM111927": {"REPLICATE": 3, "TREATED WITH": "None (control) for 6h"}}, {"GSM1119272": {"REPLICATE": 1, "TREATED WITH": "PTH(1\u201334) (10 nM) for 1h"}}, {"GSM1119273": {"REPLICATE": 2, "TREATED WITH": "PTH(1\u201334) (10 nM) for 1h"}}, {"GSM1119274": {"REPLICATE": 3, "TREATED WITH": "PTH(1\u201334) (10 nM) for 1h"}}, {"GSM1119275": {"REPLICATE": 1, "TREATED WITH": "PTH(1\u201334) (10 nM) for 24h"}}, {"GSM1119276": {"REPLICATE": 2, "TREATED WITH": "PTH(1\u201334) (10 nM) for 24h"}}, {"GSM1119277": {"REPLICATE": 3, "TREATED WITH": "PTH(1\u201334) (10 nM) for 24h"}}, {"GSM1119278": {"REPLICATE": 1, "TREATED WITH": "PTH(1\u201334) (10 nM) for 6h"}}, {"GSM1119279": {"REPLICATE": 2, "TREATED WITH": "PTH(1\u201334) (10 nM) for 6h"}}, {"GSM1119280": {"REPLICATE": 3, "TREATED WITH": "PTH(1\u201334) (10 nM) for 6h"}}, {"GSM111928": {"REPLICATE": 1, "TREATED WITH": "PTHrP(1\u2013141) (20 nM) for 1hr"}}, {"GSM1119282": {"REPLICATE": 2, "TREATED WITH": "PTHrP(1\u2013141) (20 nM) for 1hr"}}, {"GSM1119283": {"REPLICATE": 3, "TREATED WITH": "PTHrP(1\u2013141) (20 nM) for 1hr"}}, {"GSM1119284": {"REPLICATE": 1, "TREATED WITH": "PTHrP(1\u2013141) (20 nM) for 24hr"}}, {"GSM1119286": {"REPLICATE": 2, "TREATED WITH": "PTHrP(1\u2013141) (20 nM) for 24hr"}}, {"GSM1119288": {"REPLICATE": 3, "TREATED WITH": "PTHrP(1\u2013141) (20 nM) for 24hr"}}, {"GSM1119290": {"REPLICATE": 1, "TREATED WITH": "PTHrP(1\u2013141) (20 nM) for 6hr"}}, {"GSM1119293": {"REPLICATE": 2, "TREATED WITH": "PTHrP(1\u2013141) (20 nM) for 6hr"}}, {"GSM1119295": {"REPLICATE": 3, "TREATED WITH": "PTHrP(1\u2013141) (20 nM) for 6hr"}}], "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "With the aim of identifying new pathways and genes regulated by PTH(1-34) and PTH-related protein 1-141 [PTHrP(1-141)] in osteoblasts,...", "pubmed_id": 18627264, "geo_gse_id": "E-GEOD-45895", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 27, "tags": ["cell", "genome", "line", "protein", "stromal cell"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "ephrinb2-regulation-by-pth-and-pthrp-revealed-by-m", "geo_id_plat": "E-GEOD-45895_A-AFFY-45", "name": "EphrinB2 Regulation by PTH and PTHrP Revealed by Molecular Profiling in Differentiating Osteoblasts", "created": "Nov.12, 2014", "summary": "With the aim of identifying new pathways and genes regulated by PTH(1-34) and PTH-related protein 1-141 [PTHrP(1-141)] in osteoblasts, this study was carried out using a mouse marrow stromal cell line, Kusa 4b10, that acquires features of the osteoblastic phenotype in long-term culture conditions. After the appearance of functional PTH receptor 1 (PTHR1) in Kusa 4b10 cells, they were treated with either PTH(1-34) or PTHrP(1-141), and RNA was subjected to Affymetrix whole mouse genome array. Timecourse experiment on Kusa4b10 cell lines, treatment with PTH or PTHrP, collection at 1, 6 and 24 hours  NOTE: This work has been published in 2008 (PMID 18627264); Since the original normalised data for this project is unavailable,  the data has been re-normalised using a standard method for GEO submission in 2013. Therefore, the re-normalized data represented in this records may differ slightly from the original normalized data in the publication.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-45895", "species": "mouse", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-45895/samples/"}