{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSM1113543": {"ORGANISM PART": "lung", "STRAIN OR LINE": "FVB"}}, {"GSM1113543": {"ORGANISM PART": "lung", "STRAIN OR LINE": "FVB"}}, {"GSM1113543": {"ORGANISM PART": "lung", "STRAIN OR LINE": "FVB"}}, {"GSM1113543": {"ORGANISM PART": "lung", "STRAIN OR LINE": "FVB"}}, {"GSM1113547": {"ORGANISM PART": "lung", "STRAIN OR LINE": "FVB transgene human surfactant protein C promoter-driven wild-type human Cyclin E"}}, {"GSM1113547": {"ORGANISM PART": "lung", "STRAIN OR LINE": "FVB transgene human surfactant protein C promoter-driven wild-type human Cyclin E"}}, {"GSM1113547": {"ORGANISM PART": "lung", "STRAIN OR LINE": "FVB transgene human surfactant protein C promoter-driven wild-type human Cyclin E"}}, {"GSM1113547": {"ORGANISM PART": "lung", "STRAIN OR LINE": "FVB transgene human surfactant protein C promoter-driven wild-type human Cyclin E"}}, {"GSM111355": {"ORGANISM PART": "lung adenocarcinoma", "STRAIN OR LINE": "FVB transgene human surfactant protein C promoter-driven wild-type human Cyclin E"}}, {"GSM111355": {"ORGANISM PART": "lung adenocarcinoma", "STRAIN OR LINE": "FVB transgene human surfactant protein C promoter-driven wild-type human Cyclin E"}}, {"GSM111355": {"ORGANISM PART": "lung adenocarcinoma", "STRAIN OR LINE": "FVB transgene human surfactant protein C promoter-driven wild-type human Cyclin E"}}, {"GSM111355": {"ORGANISM PART": "lung adenocarcinoma", "STRAIN OR LINE": "FVB transgene human surfactant protein C promoter-driven wild-type human Cyclin E"}}], "id": 7237, "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "FVB mice were engineered to express wild-type human cyclin E under control of the human surfactant C promoter (CEO mice; Ma et al, PNAS...", "geo_gse_id": "E-GEOD-45744", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 12, "tags": ["adenocarcinoma", "genome", "lung", "protein"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "whole-genome-expression-data-from-normal-fvb-mouse", "geo_id_plat": "E-GEOD-45744_A-AFFY-45", "name": "Whole-genome expression data from normal FVB mouse lung tissue, transgenic cyclin E overexpressing (CEO) normal mouse lung tissue, and transgenic CEO lung adenocarcinomas", "created": "Nov.12, 2014", "summary": "FVB mice were engineered to express wild-type human cyclin E under control of the human surfactant C promoter (CEO mice; Ma et al, PNAS 2007).  These mice develop spontaneous lung tumors, which were shown to be adenocarcinoma by histological analysis.  Here we compare whole-genome RNA expression levels between the tumors and normal lung of 4 CEO mice as well as 4 nontransgenic animals. RNA was isolated from the lungs of 4 FVB mice and adjacent normal and tumor tissue from 4 FVB transgenes harboring human surfactant protein C- driven wild-type human cyclin E, all 7-11 months in age.  These samples were divided into 3 groups of four, and  12 independent hybridizations were performed for analysis with Affymetrix GeneChip Mouse 430 2.0 arrays.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-45744", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-45744/samples/"}