Dataset: Prevention of Mouse AA with IL-15 pathway inhibitors
Our goal was to identify gene expression patterns that correlated with prevention of autoimmune alopecia in C3H/HeJ mice following...
Our goal was to identify gene expression patterns that correlated with prevention of autoimmune alopecia in C3H/HeJ mice following alopecic graft transplantation skin from 3-5 mice were taken at 5/6 weeks and 12/13 weeks of drug administration following grafting; mice were treated with ruxolitinib (jak12i) by oral gavage, tofacitinib (jak3i) by osmotic pump, antiIL15R-beta antibody by i.p. injection, or control pbs by either ip injection, oral gavage, or osmotic pump. sham indicates mice that received no graft. 3-5 biological replicates were taken at each time point for each treatment modality
- Species:
- mouse
- Samples:
- 48
- Source:
- E-GEOD-45551
- Updated:
- Dec.12, 2014
- Registered:
- Nov.12, 2014
Factors:
(via ArrayExpress)
| Sample | WEEKS OF TREATMENT | TREATMENT |
|---|---|---|
| GSM1109116 | 5/6 | IL15 |
| GSM1109116 | 5/6 | IL15 |
| GSM1109116 | 5/6 | IL15 |
| GSM1109116 | 5/6 | IL15 |
| GSM1109120 | 5/6 | PBS- ip |
| GSM1109120 | 5/6 | PBS- ip |
| GSM1109120 | 5/6 | PBS- ip |
| GSM1109120 | 5/6 | PBS- ip |
| GSM1109124 | 5/6 | sham |
| GSM1109124 | 5/6 | sham |
| GSM1109124 | 5/6 | sham |
| GSM1109124 | 5/6 | sham |
| GSM1109128 | 5/6 | jak3i |
| GSM1109128 | 5/6 | jak3i |
| GSM1109128 | 5/6 | jak3i |
| GSM1109128 | 5/6 | jak3i |
| GSM1109128 | 5/6 | jak3i |
| GSM1109133 | 5/6 | jak12i |
| GSM1109133 | 5/6 | jak12i |
| GSM1109133 | 5/6 | jak12i |
| GSM1109133 | 5/6 | jak12i |
| GSM1109133 | 5/6 | jak12i |
| GSM1109138 | 5/6 | PBS- pump |
| GSM1109138 | 5/6 | PBS- pump |
| GSM1109138 | 5/6 | PBS- pump |
| GSM110914 | 5/6 | PBS- gavage |
| GSM110914 | 5/6 | PBS- gavage |
| GSM110914 | 5/6 | PBS- gavage |
| GSM110914 | 5/6 | PBS- gavage |
| GSM110914 | 5/6 | PBS- gavage |
| GSM1109146 | 12/13 | IL15 |
| GSM1109146 | 12/13 | IL15 |
| GSM1109146 | 12/13 | IL15 |
| GSM1109149 | 12/13 | jak3i |
| GSM1109149 | 12/13 | jak3i |
| GSM1109149 | 12/13 | jak3i |
| GSM1109152 | 12/13 | jak12i |
| GSM1109152 | 12/13 | jak12i |
| GSM1109152 | 12/13 | jak12i |
| GSM1109155 | 12/13 | PBS- ip |
| GSM1109155 | 12/13 | PBS- ip |
| GSM1109155 | 12/13 | PBS- ip |
| GSM1109158 | 12/13 | PBS- pump |
| GSM1109158 | 12/13 | PBS- pump |
| GSM1109158 | 12/13 | PBS- pump |
| GSM110916 | 12/13 | PBS- gavage |
| GSM110916 | 12/13 | PBS- gavage |
| GSM110916 | 12/13 | PBS- gavage |