{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSM1076145": {"CELL": "p53-/- mouse fetal liver progenitor cells", "TRANSFORMATION": "non-transformed"}}, {"GSM1076146": {"CELL": "p53-/- mouse fetal liver progenitor cells transformed with H-RasV12", "TRANSFORMATION": "H-RasV12"}}, {"GSM1076147": {"CELL": "p53-/- mouse fetal liver progenitor cells transformed with myr-Akt", "TRANSFORMATION": "myr-Akt"}}, {"GSM1076148": {"CELL": "p53-/- mouse fetal liver progenitor cells transformed with c-Myc", "TRANSFORMATION": "c-Myc"}}], "id": 7160, "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "The activation of different oncogenic signals may primarily contribute to the heterogeneity of cancer cells. However, the exact...", "geo_gse_id": "E-GEOD-43991", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 4, "tags": ["cancer", "cell", "liver", "liver cell"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "differentially-expressed-genes-between-oncogene-tr", "geo_id_plat": "E-GEOD-43991_A-AFFY-45", "name": "Differentially expressed genes between oncogene-transformed and non-transformed fetal liver progenitor cells", "created": "Nov.12, 2014", "summary": "The activation of different oncogenic signals may primarily contribute to the heterogeneity of cancer cells. However, the exact mechanisms underlying different oncogenic transformation are still unclear. We used the c-Myc, H-Ras and Akt transformed liver cell model to define mRNA expression profiles in the non-transformed and the three types of oncogene-transformed cells Purified p53-/- mouse fetal liver progenitor cells were transformed by three oncogenic genetic factors, c-Myc, H-RasV12 and myristoylated-AKT1(myr-Akt). The gene expression profilings of transformed cells and control cells were analyzed through microarray.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-43991", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-43991/samples/"}