ArrayExpress Uploaderarrayexpress_sidmousewild typewild typewild typeE2A deficientE2A deficientE2A deficient712306The E2A transcription factors promote the development of thymus-seeding cells but it remains unknown whether these proteins play a role...23297135E-GEOD-43224/profile/8773/arrayexpressuploader16lymphocytet lymphocytethymusDec.12, 2014FalseE-GEOD-43224_A-AFFY-45expression-data-from-wt-and-e2a-deficient-murine-dExpression data from WT and E2A-deficient murine DN2 cellsNov.12, 2014The E2A transcription factors promote the development of thymus-seeding cells but it remains unknown whether these proteins play a role in T lymphocyte lineage specification or commitment. By examining E2A-dependent genes in developing T cells, we will address whether these proteins are involved in these processes. DN2 cells from WT and E2A-deficient murine fetal thymi were FACS sorted. Subsequently RNA was extracted, labelled and hybridized to Affymetrix microarrays. The goal of this study is to investigate E2A-dependent genes in developing T cellshttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-43224http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-43224/samples/