ArrayExpress Uploader0humannon-bortezomib-based mobilizationnon-bortezomib-based mobilizationnon-bortezomib-based mobilizationbortezomib-based mobilizationbortezomib-based mobilizationbortezomib-based mobilizationbortezomib-based mobilizationbortezomib-based mobilization2541arrayexpress_sid4Bortezomib-based secondary induction therapy and mobilization could represent alternative strategies to reduce tumor burden. We used...E-GEOD-43124/profile/8773/arrayexpressuploader18cellgenomemultiple myelomamyelomastem cellDec.12, 2014Falseexpression-data-from-mobilized-human-cd34-cellsE-GEOD-43124_A-AFFY-44Expression data from mobilized human CD34+ cellsJul.12, 2014Bortezomib-based secondary induction therapy and mobilization could represent alternative strategies to reduce tumor burden. We used microarrays to investigate genome-wide expression changes between bortezomib and non-bortzomib mobilizaton strategies and identified distinct genes and pathways that were significantly differentially regulated. CD34+ stem cells were enriched from leukapheresis products from multiple myeloma patients treated with a bortezomib- or non-bortezomib-based mobilization. RNA extraction, amplification and hybridization on Affymetrix microarrays was performed. Post-induction stem cell collection was initiated when patients' ANC reached >1.0×10^9/L.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-43124http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-43124/samples/