{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSM1057009": {"TREATMENT": "non-bortezomib-based mobilization"}}, {"GSM1057009": {"TREATMENT": "non-bortezomib-based mobilization"}}, {"GSM1057009": {"TREATMENT": "non-bortezomib-based mobilization"}}, {"GSM1057006": {"TREATMENT": "bortezomib-based mobilization"}}, {"GSM1057006": {"TREATMENT": "bortezomib-based mobilization"}}, {"GSM1057006": {"TREATMENT": "bortezomib-based mobilization"}}, {"GSM1057006": {"TREATMENT": "bortezomib-based mobilization"}}, {"GSM1057006": {"TREATMENT": "bortezomib-based mobilization"}}], "id": 2541, "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "Bortezomib-based secondary induction therapy and mobilization could represent alternative strategies to reduce tumor burden. We used...", "geo_gse_id": "E-GEOD-43124", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 8, "tags": ["cell", "genome", "multiple myeloma", "myeloma", "stem cell"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "expression-data-from-mobilized-human-cd34-cells", "geo_id_plat": "E-GEOD-43124_A-AFFY-44", "name": "Expression data from mobilized human CD34+ cells", "created": "Jul.12, 2014", "summary": "Bortezomib-based secondary induction therapy and mobilization could represent alternative strategies to reduce tumor burden. We used microarrays to investigate genome-wide expression changes between bortezomib and non-bortzomib mobilizaton strategies and identified distinct genes and pathways that were significantly differentially regulated. CD34+ stem cells were enriched from leukapheresis products from multiple myeloma patients treated with a bortezomib- or non-bortezomib-based mobilization. RNA extraction, amplification and hybridization on Affymetrix microarrays was performed. Post-induction stem cell collection was initiated when patients' ANC reached >1.0\u00d710^9/L.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-43124", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-43124/samples/"}