{"platform": 4, "owner": "ArrayExpress Uploader", "pop_total": 0, "id": 2479, "factors": [{"GSM1055799 1": {}}], "ownerprofile_id": "arrayexpress_sid", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-43068", "summary_wrapped": "The MLL gene on chromosome 11 fuses to the AF6 gene on chromosome 6 in a balanced chromosomal translocation that is characetristic of...", "pubmed_id": 23361907, "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 0, "sample_count": 1, "tags": ["bone", "bone marrow", "cell", "chromosome", "leukemia", "line"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "expression-data-from-a-human-mll-af6-positive-aml", "geo_id_plat": "E-GEOD-43068_A-AFFY-44", "name": "Expression data from a human MLL-AF6 positive AML cell line", "created": "Jul.12, 2014", "summary": "The MLL gene on chromosome 11 fuses to the AF6 gene on chromosome 6 in a balanced chromosomal translocation that is characetristic of certain adult and pediatric human leukemias. We established a murine leukemia model of MLL-AF6 using the retroviral MLL-AF6 contruct in a bone marrow transplantation system. The ML2 human MLL-AF6 positive leukemia cell line was used for gene expression profiling to assess the transctiptional profile in MLL-AF6 leukemias. RNA was extracted from the ML2 cell line cultured under standard conditionswith TRIZOL (Invitrogen), purified using RNAeasy(Qiagen) and hybridized onto Affymetrix arrays.", "geo_gse_id": "E-GEOD-43068", "species": "human", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-43068/samples/"}