Dataset: Expression data from MLL-AF6 positive leukemia cells

The MLL gene on chromosome 11 fuses to the AF6 gene on chromosome 6 in a balanced chromosomal translocation that is characetristic of certain adult and pediatric human leukemias. We established a murine leukemia model of MLL-AF6 using the retroviral MLL-AF6 contruct in a bone marrow transplantation system. Leukemic bone marrow cells from a sacrificed moribund mouse were thawed and RNA was extracted using TRIZOL (Invitrogen) and purified further using the RNAeasy kit (Qiagen) under standard conditions and and hybridized onto Affymetrix arrays.

Species:

mouse

Samples:

3

Source:

E-GEOD-43067

PubMed:

23361907

Updated:

Dec.12, 2014

Registered:

Nov.12, 2014