{"owner": "ArrayExpress Uploader", "pop_total": 0, "id": 2645, "factors": [{"GSM1051327": {"CD4 RESPONSE TO ANTIGENS": "Candida Albicans+"}}, {"GSM1051326": {"CD4 RESPONSE TO ANTIGENS": "Tetanus toxoid+"}}, {"GSM1051325": {"CD4 RESPONSE TO ANTIGENS": "CMV+"}}, {"GSM1051327": {"CD4 RESPONSE TO ANTIGENS": "Candida Albicans+"}}, {"GSM1051326": {"CD4 RESPONSE TO ANTIGENS": "Tetanus toxoid+"}}, {"GSM1051325": {"CD4 RESPONSE TO ANTIGENS": "CMV+"}}, {"GSM1051327": {"CD4 RESPONSE TO ANTIGENS": "Candida Albicans+"}}, {"GSM1051326": {"CD4 RESPONSE TO ANTIGENS": "Tetanus toxoid+"}}, {"GSM1051325": {"CD4 RESPONSE TO ANTIGENS": "CMV+"}}], "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "Analysis of global gene expression profiles of flow cytometry-sorted, different pathogen-specific CD4+ T cell populations from the same...", "pubmed_id": 23258923, "geo_gse_id": "E-GEOD-42853", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 9, "tags": ["cell", "hiv infection", "peripheral", "tetanus"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "distinct-gene-expression-profiles-associated-with", "geo_id_plat": "E-GEOD-42853_A-AFFY-44", "name": "Distinct gene expression profiles associated with the susceptibility of pathogen-specific CD4 T cells to HIV-1 infection", "created": "Jul.12, 2014", "summary": "Analysis of global gene expression profiles of flow cytometry-sorted, different pathogen-specific CD4+ T cell populations from the same peripheral blood mononuclear cells (PBMC), to identify molecular parameters that regulate differential susceptibilities of these CD4+ T cells to HIV infection. The results reveal distinct gene expression profiles between CMV-specific and tetanus toxoid/Candida-specific CD4+ T cells that involved selective upregulation of comprehensive innate antiviral Total RNA extracted from CFSE-low, flow-sorted pathogen-specific CD4+ T cells were analyzed for global gene expression. Changes in gene expression were compared between CMV to combined TT/Candida, or TT/CMV and Candida/CMV.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-42853", "species": "human", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-42853/samples/"}