ArrayExpress Uploader07099wild-typeShn-2 mutantwild-typeShn-2 mutantwild-typeShn-2 mutantwild-typeShn-2 mutantShn-2 mutantwild-typewild-typeShn-2 mutantarrayexpress_sid6Schnurri-2 (Shn-2), an NF-kappa B site-binding protein, tightly binds to the enhancers of major histocompatibility complex (MHC) class I...23389689/profile/8773/arrayexpressuploader112classmajor histocompatibility complexnucleotideproteinschizophreniaDec.12, 2014FalseE-GEOD-42777_A-AFFY-45gene-expression-microarray-analysis-on-the-dentatehttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-42777Gene expression microarray analysis on the dentate gyrus of Schnurri-2 knockout and wild-type control miceNov.12, 2014Schnurri-2 (Shn-2), an NF-kappa B site-binding protein, tightly binds to the enhancers of major histocompatibility complex (MHC) class I genes and inflammatory cytokines, which have been shown to harbor common variant single nucleotide polymorphisms associated with schizophrenia. Shn-2 knockout mice show behavioral abnormalities that strongly resemble those of schizophrenics. We performed gene expression microarray analysis of dentate gyri from Shn-2 knockout and wild-type control mice. Dentate gyrus RNA isolated from six Shn-2 knockout and six control wild-type mice were compared.E-GEOD-42777mousehttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-42777/samples/