{"owner": "ArrayExpress Uploader", "pop_total": 0, "id": 7098, "factors": [{"GSM1049758": {"GENOTYPE": "wild-type"}}, {"GSM1049759": {"GENOTYPE": "Shn-2 mutant"}}, {"GSM1049758": {"GENOTYPE": "wild-type"}}, {"GSM1049759": {"GENOTYPE": "Shn-2 mutant"}}, {"GSM1049758": {"GENOTYPE": "wild-type"}}, {"GSM1049759": {"GENOTYPE": "Shn-2 mutant"}}, {"GSM1049758": {"GENOTYPE": "wild-type"}}, {"GSM1049759": {"GENOTYPE": "Shn-2 mutant"}}, {"GSM1049759": {"GENOTYPE": "Shn-2 mutant"}}, {"GSM1049758": {"GENOTYPE": "wild-type"}}, {"GSM1049758": {"GENOTYPE": "wild-type"}}, {"GSM1049759": {"GENOTYPE": "Shn-2 mutant"}}], "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "Schnurri-2 (Shn-2), an NF-kappa B site-binding protein, tightly binds to the enhancers of major histocompatibility complex (MHC) class I...", "pubmed_id": 23389689, "geo_gse_id": "E-GEOD-42775", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 12, "tags": ["class", "cortex", "major histocompatibility complex", "nucleotide", "prefrontal cortex", "protein", "schizophrenia"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_id_plat": "E-GEOD-42775_A-AFFY-45", "slug": "gene-expression-microarray-analysis-on-the-medial", "geo_gds_id": "", "name": "Gene expression microarray analysis on the medial prefrontal cortex of Schnurri-2 knockout and wild-type control mice", "created": "Nov.12, 2014", "summary": "Schnurri-2 (Shn-2), an NF-kappa B site-binding protein, tightly binds to the enhancers of major histocompatibility complex (MHC) class I genes and inflammatory cytokines, which have been shown to harbor common variant single nucleotide polymorphisms associated with schizophrenia. Shn-2 knockout mice show behavioral abnormalities that strongly resemble those of schizophrenics. We performed gene expression microarray analysis of prefrontal cortices from Shn-2 knockout and wild-type control mice. Prefrontal cortex RNA isolated from six Shn-2 knockout and six control wild-type mice were compared.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-42775", "species": "mouse", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-42775/samples/"}