ArrayExpress Uploaderarrayexpress_sidhumanHealthy donorpurified CD14 monocyteHealthy donorpurified CD14 monocyteHealthy donorpurified CD14 monocyteHealthy donorpurified CD14 monocyteHealthy donorpurified CD14 monocytechronic lymphocytic leukemiapurified nurse-like cellchronic lymphocytic leukemiapurified nurse-like cellchronic lymphocytic leukemiapurified nurse-like cellchronic lymphocytic leukemiapurified nurse-like cellchronic lymphocytic leukemiapurified nurse-like cellchronic lymphocytic leukemiapurified nurse-like cellchronic lymphocytic leukemiapurified nurse-like cellchronic lymphocytic leukemiapurified nurse-like cellchronic lymphocytic leukemiapurified nurse-like cellchronic lymphocytic leukemiapurified nurse-like cell265504The study of the roles of macrophages in the microenvironment of cancer cells (tumor-associated macrophages, TAM) has gained deep insight...E-GEOD-42733/profile/8773/arrayexpressuploader215cancerchronic lymphocytic leukemiadeepleukemiaDec.12, 2014Falsegene-expression-profile-of-nurse-like-cells-nlc-deE-GEOD-42733_A-AFFY-44Gene expression profile of Nurse-Like Cells (NLC) derived from chronic lymphocytic leukemiaJul.12, 2014The study of the roles of macrophages in the microenvironment of cancer cells (tumor-associated macrophages, TAM) has gained deep insight over the recent years. Here, we describe gene expression profile of chronic lymphocytic leukemia (CLL)-associated macrophages, also called nurse-like cells (NLC), derived from in vitro co-cultures system. We define these NLC as M2-oriented, TAM-like specific subset of macrophages, with very few inter-individual variations in gene expression profiles. CLL patients PBMC were isolated and cultured for 15 days in vitro. NLC were then isolated, mRNA were purified and hybridized on Affymetrix U133 plus 2.0 chips. Data were normalized by RMA5http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-42733http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-42733/samples/