{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSM1047770": {"CELL LINE": "CRL-2097", "CELL TYPE": "Induced endothelial cells"}}, {"GSM104777": {"CELL LINE": "BJ", "CELL TYPE": "Induced endothelial cells"}}, {"GSM1047772": {"CELL LINE": "not specified", "CELL TYPE": "human umbilical vein endothelial cell"}}, {"GSM1047773": {"CELL LINE": "not specified", "CELL TYPE": "fibroblast"}}], "id": 4615, "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "Transient pluripotency-factor-based signaling-directed (TPS) transdifferentiation  approach could be further applied to generate...", "geo_gse_id": "E-GEOD-42672", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 4, "tags": ["cell", "cell phenotype", "endothelial cell"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "conversion-of-human-fibroblast-to-endothelial-cell", "geo_id_plat": "E-GEOD-42672_A-AFFY-44", "name": "Conversion of human fibroblast to endothelial cell by defined factors", "created": "Sep.19, 2014", "summary": "Transient pluripotency-factor-based signaling-directed (TPS) transdifferentiation  approach could be further applied to generate functional induced endothelial (iEnd) cells  from human fibroblasts with only two factors: Oct4 and Klf4 (OK). The iEnd cells exhibit  characteristic endothelial cell phenotype in vitro and in vivo and are capable of functionally  promoting vascular regeneration and blood perfusion in a murine model of PAD. Human fibroblasts were transfected with Oct4 and Klf4 then changed to endothelial cell culture media with growth factors. iENDs were purified by FACS and enriched in EGM2 media.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-42672", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-42672/samples/"}