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<biogps><data><item key="owner">ArrayExpress Uploader</item><item key="pop_total">0</item><item key="id">7085</item><item key="factors"><item><item key="GSM1040577"><item key="SHRNA">Vector control</item></item></item><item><item key="GSM1040578"><item key="SHRNA">shPhf19</item></item></item><item><item key="GSM1040577"><item key="SHRNA">Vector control</item></item></item><item><item key="GSM1040578"><item key="SHRNA">shPhf19</item></item></item></item><item key="ownerprofile_id">arrayexpress_sid</item><item key="platform">6</item><item key="summary_wrapped">PCL family protein Phf19/Pcl3 is one of the accessory components of the PRC2 core complex, and Phf19 is highly expressed in murine ES...</item><item key="pubmed_id">23273982</item><item key="owner_profile">/profile/8773/arrayexpressuploader</item><item key="factor_count">1</item><item key="sample_count">4</item><item key="tags"><item>carcinoma</item><item>cell</item><item>embryonal carcinoma</item><item>line</item><item>protein</item></item><item key="lastmodified">Dec.12, 2014</item><item key="is_default">False</item><item key="geo_id_plat">E-GEOD-42463_A-AFFY-45</item><item key="slug">phf19-knockdown-effect-on-f9-embryonal-carcinoma-c</item><item key="source">http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-42463</item><item key="geo_gds_id"/><item key="name">Phf19 knockdown effect on F9 embryonal carcinoma cells</item><item key="created">Nov.12, 2014</item><item key="summary">PCL family protein Phf19/Pcl3 is one of the accessory components of the PRC2 core complex, and Phf19 is highly expressed in murine ES cells and an ES cell-like embryonic carcinoma cell line, F9 cells. Here we performed microarray analysis of embryonal carcinoma cell line F9 following Phf19 knockdown by shRNA. Knocking down Phf19/Pcl3 in F9 embryonic cells led to derepression of numerous PRC2 direct target genes. 4 sampels including 2 shRNA vector control cell lines and 2 shPhf19 cell lines were used for RNA extraction and Affymetrix mouse 430 2.0 arrays.</item><item key="geo_gse_id">E-GEOD-42463</item><item key="species">mouse</item><item key="sample_source">http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-42463/samples/</item></data></biogps>
