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Home › Dataset Library › Nitric Oxide-releasing prodrug triggers cancer cell death through deregulation of cellular redox balance

Dataset: Nitric Oxide-releasing prodrug triggers cancer cell death through deregulation of cellular redox balance

JS-K, a NO donor which capable to induce cancer apopotosis, it's killing mechanism was investigated in this study. We found out that JS-K...

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JS-K, a NO donor which capable to induce cancer apopotosis, it's killing mechanism was investigated in this study. We found out that JS-K induce apopotosis via deregulating the GSH/GSSG redox couple. Leukemia cells were treated with JS-K and then assayed for metabolic changes by LC/MS and gene expression alterations by microarray.

Species:
human

Samples:
12

Source:
E-GEOD-42344

Updated:
Dec.12, 2014

Registered:
Jul.12, 2014


Factors: (via ArrayExpress)
Sample
GSM1038179 1
GSM1038178 1
GSM1038177 1
GSM1038176 1
GSM1038175 1
GSM1038174 1
GSM1038173 1
GSM1038172 1
GSM1038171 1
GSM1038170 1
GSM1038169 1
GSM1038168 1

Tags

  • cancer
  • leukemia

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