{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSM1035822": {"INDIVIDUAL ID": "3", "CELL TYPE": "single sorted initial leukemia"}}, {"GSM103582": {"INDIVIDUAL ID": "2", "CELL TYPE": "single sorted initial leukemia"}}, {"GSM1035820": {"INDIVIDUAL ID": "1", "CELL TYPE": "single sorted initial leukemia"}}, {"GSM1035819": {"INDIVIDUAL ID": "4", "CELL TYPE": "single sorted lymphoblasts in complete continuous remission"}}, {"GSM1035818": {"INDIVIDUAL ID": "3", "CELL TYPE": "single sorted lymphoblasts in complete continuous remission"}}, {"GSM1035817": {"INDIVIDUAL ID": "2", "CELL TYPE": "single sorted lymphoblasts in complete continuous remission"}}, {"GSM1035816": {"INDIVIDUAL ID": "1", "CELL TYPE": "single sorted lymphoblasts in complete continuous remission"}}, {"GSM1035815": {"INDIVIDUAL ID": "4", "CELL TYPE": "Initial, untreated leukemia"}}, {"GSM1035814": {"INDIVIDUAL ID": "3", "CELL TYPE": "Initial, untreated leukemia"}}, {"GSM1035813": {"INDIVIDUAL ID": "2", "CELL TYPE": "Initial, untreated leukemia"}}, {"GSM1035812": {"INDIVIDUAL ID": "1", "CELL TYPE": "Initial, untreated leukemia"}}], "id": 1215, "ownerprofile_id": "arrayexpress_sid", "platform": 3, "summary_wrapped": "The objective of this study was the assessment of transcriptional dysregulation in particular with regard to B-cell differentiation...", "geo_gse_id": "E-GEOD-42221", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 11, "tags": ["cell", "leukemia"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "comparative-intraindividual-transcriptome-analysis", "geo_id_plat": "E-GEOD-42221_A-AFFY-33", "name": "Comparative intraindividual transcriptome analysis of B-precursor ALL of childhood", "created": "Jun.18, 2014", "summary": "The objective of this study was the assessment of transcriptional dysregulation in particular with regard to B-cell differentiation factors. Most studies focus on cross-section analyses of various leukemia subtypes to identify differentially regulated genes lacking suitable reference models. Here we applied comparative intraindividual transcriptome analysis of B-precursor ALL of childhood, which introduces a side-by-side analysis of leukemic cells and matched normal lymphoblasts from the same individual in complete continuous remission after the end of re-induction therapy. This approach reduces noise by eliminating interindividual variability. Comparative matched pair analysis of (single sorted) initial leukemia and single sorted lymphoblasts isolated from the same individual, n=4 pairs, reference samples are the single sorted normal lymphoblasts. Please note that there are sorted samples form only three of the patients. Due to experimental circumstances, a \"sorted\" sample from the last patient was not included.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-42221", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-42221/samples/"}