{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSM1030709": {"ORGANISM PART": "Lymphnode", "CELL SUBTYPE": "peri Treg"}}, {"GSM1030710": {"ORGANISM PART": "Lymphnode", "CELL SUBTYPE": "peri naive Tcell"}}, {"GSM10307": {"ORGANISM PART": "thymus", "CELL SUBTYPE": "Treg precursor cell"}}, {"GSM1030712": {"ORGANISM PART": "thymus", "CELL SUBTYPE": "Treg Foxp3+GFP+  CD24hi"}}, {"GSM1030713": {"ORGANISM PART": "thymus", "CELL SUBTYPE": "Treg Foxp3+GFP+  CD24int"}}, {"GSM1030714": {"ORGANISM PART": "thymus", "CELL SUBTYPE": "Treg Foxp3+GFP+  CD24low"}}, {"GSM1030715": {"ORGANISM PART": "thymus", "CELL SUBTYPE": "Treg Foxp3-GFP-  CD24hi"}}, {"GSM1030716": {"ORGANISM PART": "thymus", "CELL SUBTYPE": "Treg Foxp3-GFP-  CD24intermediate"}}, {"GSM1030717": {"ORGANISM PART": "thymus", "CELL SUBTYPE": "Treg Foxp3-GFP-  CD24low"}}, {"GSM1030709": {"ORGANISM PART": "Lymphnode", "CELL SUBTYPE": "peri Treg"}}, {"GSM1030710": {"ORGANISM PART": "Lymphnode", "CELL SUBTYPE": "peri naive Tcell"}}, {"GSM10307": {"ORGANISM PART": "thymus", "CELL SUBTYPE": "Treg precursor cell"}}, {"GSM1030712": {"ORGANISM PART": "thymus", "CELL SUBTYPE": "Treg Foxp3+GFP+  CD24hi"}}, {"GSM1030713": {"ORGANISM PART": "thymus", "CELL SUBTYPE": "Treg Foxp3+GFP+  CD24int"}}, {"GSM1030714": {"ORGANISM PART": "thymus", "CELL SUBTYPE": "Treg Foxp3+GFP+  CD24low"}}, {"GSM1030715": {"ORGANISM PART": "thymus", "CELL SUBTYPE": "Treg Foxp3-GFP-  CD24hi"}}, {"GSM1030716": {"ORGANISM PART": "thymus", "CELL SUBTYPE": "Treg Foxp3-GFP-  CD24intermediate"}}, {"GSM1030717": {"ORGANISM PART": "thymus", "CELL SUBTYPE": "Treg Foxp3-GFP-  CD24low"}}, {"GSM1030709": {"ORGANISM PART": "Lymphnode", "CELL SUBTYPE": "peri Treg"}}, {"GSM1030710": {"ORGANISM PART": "Lymphnode", "CELL SUBTYPE": "peri naive Tcell"}}, {"GSM10307": {"ORGANISM PART": "thymus", "CELL SUBTYPE": "Treg precursor cell"}}, {"GSM1030712": {"ORGANISM PART": "thymus", "CELL SUBTYPE": "Treg Foxp3+GFP+  CD24hi"}}, {"GSM1030713": {"ORGANISM PART": "thymus", "CELL SUBTYPE": "Treg Foxp3+GFP+  CD24int"}}, {"GSM1030714": {"ORGANISM PART": "thymus", "CELL SUBTYPE": "Treg Foxp3+GFP+  CD24low"}}, {"GSM1030715": {"ORGANISM PART": "thymus", "CELL SUBTYPE": "Treg Foxp3-GFP-  CD24hi"}}, {"GSM1030716": {"ORGANISM PART": "thymus", "CELL SUBTYPE": "Treg Foxp3-GFP-  CD24intermediate"}}, {"GSM1030717": {"ORGANISM PART": "thymus", "CELL SUBTYPE": "Treg Foxp3-GFP-  CD24low"}}], "id": 7072, "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "We  investigated at which stage of maturation commitment to a stable Foxp3-expressing phenotype takes place. We assessed stability of...", "pubmed_id": 23420886, "geo_gse_id": "E-GEOD-42021", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 27, "tags": [], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_id_plat": "E-GEOD-42021_A-AFFY-45", "slug": "gene-expression-profiles-of-cd4sp-foxp3gfp-cd25-tr", "geo_gds_id": "", "name": "Gene expression profiles of CD4SP Foxp3GFP-CD25+ Treg precursors and Foxp3GFP-CD25- thymocytes", "created": "Nov.12, 2014", "summary": "We  investigated at which stage of maturation commitment to a stable Foxp3-expressing phenotype takes place. We assessed stability of Foxp3 expression in thymic Foxp3+ Treg subsets of different maturity, defined by CD24 expression. Next we compared gene expression profiles of Foxp3+ Treg subsets (+) of different maturity (24lo, 24int, 24hi) and could identify a set of genes that were specifically up or downregulated in Foxp3+ Tregs, but not in Foxp3- conventional T cells, in a maturation-dependent manner. Gene expression of Foxp3+ Treg subsets (+) of different maturity (24lo, 24int, 24hi) compared to their  Foxp3- conventional Tcell subsets (-) counterpart.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-42021", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-42021/samples/"}