{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSM1012668": {"VARIATION": "Six3Cre-;Fgfr1fx/fx;Fgfr2fx/fx (control)"}}, {"GSM1012668": {"VARIATION": "Six3Cre-;Fgfr1fx/fx;Fgfr2fx/fx (control)"}}, {"GSM1012668": {"VARIATION": "Six3Cre-;Fgfr1fx/fx;Fgfr2fx/fx (control)"}}, {"GSM101267": {"VARIATION": "Six3Cre+;Fgfr1fx/fx;Fgfr2fx/fx (FGFR mutant)"}}, {"GSM101267": {"VARIATION": "Six3Cre+;Fgfr1fx/fx;Fgfr2fx/fx (FGFR mutant)"}}, {"GSM101267": {"VARIATION": "Six3Cre+;Fgfr1fx/fx;Fgfr2fx/fx (FGFR mutant)"}}], "id": 7036, "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "Mice that are mutant for both Fgfr1 and Fgfr2 specifically in the developing retina develop coloboma. To analyze the transcripts that are...", "geo_gse_id": "E-GEOD-41260", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 6, "tags": ["coloboma", "fissure", "retina"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "expression-profiles-of-e115-mouse-optic-fissure", "geo_id_plat": "E-GEOD-41260_A-AFFY-45", "name": "Expression Profiles of E11.5 Mouse Optic Fissure", "created": "Nov.12, 2014", "summary": "Mice that are mutant for both Fgfr1 and Fgfr2 specifically in the developing retina develop coloboma. To analyze the transcripts that are affected by defective FGF signaling, we micro-dissected the optic fissure region from the control and FGFR condtional mutant mice and did microarray analysis. E11.5 control and Six3Cre+; Fgfr1fx/fx;Fgfr2 fx/fx optic fissures are dissected using laser-assisted micro-dissection microscope, RNAs are extracted and labelled and hybridyzed to chips", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-41260", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-41260/samples/"}