ArrayExpress Uploader0mouseLin-c-Kit+Sca-1- cells isolated from small intestinal LPLin-c-Kit-Sca-1- cells isolated from small intestinal LP7022arrayexpress_sid6Small intestinal innate lymphoid cells (ILCs) are known to regulate intestinal epithelial cell homeostasis and to help prevent pathogenic...E-GEOD-40882/profile/8773/arrayexpressuploader12cellepithelial celllamina propriaDec.12, 2014FalseE-GEOD-40882_A-AFFY-45expression-data-from-small-intestinal-lin-c-kitscaExpression data from small intestinal Lin-c-Kit+Sca-1- cells and Lin-c-Kit-Sca-1- cells.Nov.12, 2014Small intestinal innate lymphoid cells (ILCs) are known to regulate intestinal epithelial cell homeostasis and to help prevent pathogenic bacterial infections, by producing IL-22. However, other functions of these cells and the lineal relationship between ILCs and lymphoid or myeloid cells have not been clear. We performed a global gene expression analysis to examine which genes are highly expressed by small intestinal ILCs (Lin-c-Kit+Sca-1- cells) compared with non-ILCs (Lin-c-Kit-Sca-1- cells). To examine the gene expression profiles of ILCs within the small intestinal lamina propria (LP), we isolated Lingeage (Lin)-c-Kit+Sca-1- cells [consisting of NKp46+ ILC22 (Lin-c-Kit+Sca-1-NKp46+ cells) and LTi-like ILC (Lin-c-Kit+Sca-1-CD4+ cells)] as the ILC population, and Lin-c-Kit-Sca-1- cells as the non-ILC population, from the small intestinal LP of 8 week-old mice by FACS, then compared the gene expression profiles between these two populations by microarray analysis.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-40882http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-40882/samples/