{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSM1004076": {"CELL TYPE": "Lin-c-Kit+Sca-1- cells isolated from small intestinal LP"}}, {"GSM1004077": {"CELL TYPE": "Lin-c-Kit-Sca-1- cells isolated from small intestinal LP"}}], "id": 7022, "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "Small intestinal innate lymphoid cells (ILCs) are known to regulate intestinal epithelial cell homeostasis and to help prevent pathogenic...", "geo_gse_id": "E-GEOD-40882", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 2, "tags": ["cell", "epithelial cell", "lamina propria"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_id_plat": "E-GEOD-40882_A-AFFY-45", "slug": "expression-data-from-small-intestinal-lin-c-kitsca", "geo_gds_id": "", "name": "Expression data from small intestinal Lin-c-Kit+Sca-1- cells and Lin-c-Kit-Sca-1- cells.", "created": "Nov.12, 2014", "summary": "Small intestinal innate lymphoid cells (ILCs) are known to regulate intestinal epithelial cell homeostasis and to help prevent pathogenic bacterial infections, by producing IL-22. However, other functions of these cells and the lineal relationship between ILCs and lymphoid or myeloid cells have not been clear. We performed a global gene expression analysis to examine which genes are highly expressed by small intestinal ILCs (Lin-c-Kit+Sca-1- cells) compared with non-ILCs (Lin-c-Kit-Sca-1- cells). To examine the gene expression profiles of ILCs within the small intestinal lamina propria (LP), we isolated Lingeage (Lin)-c-Kit+Sca-1- cells [consisting of NKp46+ ILC22 (Lin-c-Kit+Sca-1-NKp46+ cells) and LTi-like ILC (Lin-c-Kit+Sca-1-CD4+ cells)] as the ILC population, and Lin-c-Kit-Sca-1- cells as the non-ILC population, from the small intestinal LP of 8 week-old mice by FACS, then compared the gene expression profiles between these two populations by microarray analysis.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-40882", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-40882/samples/"}