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Home › Dataset Library › Expression data comparing adult human islets to human embryonic stem cell-derived insulin-positive and insulin-negative cells

Dataset: Expression data comparing adult human islets to human embryonic stem cell-derived insulin-positive and insulin-negative cells

The study was completed to compare expression profiles of primary human beta cells (in the form of adult human islets), to the expression...

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The study was completed to compare expression profiles of primary human beta cells (in the form of adult human islets), to the expression profile of hESC-derived beta-like cells. A HES3 line modified by homologous recombination to express GFP under the insulin promoter allowed us to FACS sort the hESC-derived cells into purified insulin-positive (presumably beta-like cells), and insulin-negative populations. Expression profile of adult human islets from cadaveric donors is compared to insulin-positive and insulin-negative populations of hESC-derived beta-like cells

Species:
human

Samples:
9

Source:
E-GEOD-40709

Updated:
Dec.12, 2014

Registered:
Sep.19, 2014


Factors: (via ArrayExpress)
Sample CELL TYPE CELL POPULATION
GSM999550 pancreatic islet not specified
GSM999550 pancreatic islet not specified
GSM999550 pancreatic islet not specified
GSM999553 hESC-derived beta-like cells insulin-positive
GSM999553 hESC-derived beta-like cells insulin-positive
GSM999553 hESC-derived beta-like cells insulin-positive
GSM999556 hESC-derived beta-like cells insulin-negative
GSM999556 hESC-derived beta-like cells insulin-negative
GSM999556 hESC-derived beta-like cells insulin-negative

Tags

  • insulin
  • line

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