{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSM993410": {"TREATMENT": "TNF (10ng/mL)+IL-17 (200ng/mL)", "TIME": "48 hour cyotkine treatment"}}, {"GSM993409": {"TREATMENT": "TNF (10ng/mL)+IL-17 (20ng/mL)", "TIME": "48 hour cyotkine treatment"}}, {"GSM993408": {"TREATMENT": "IL-17 (200ng/mL)", "TIME": "48 hour cyotkine treatment"}}, {"GSM993407": {"TREATMENT": "IL-17 (20ng/mL)", "TIME": "48 hour cyotkine treatment"}}, {"GSM993406": {"TREATMENT": "TNF (10ng/mL)", "TIME": "48 hour cyotkine treatment"}}, {"GSM993405": {"TREATMENT": "Ctrl", "TIME": "48 hour cyotkine treatment"}}, {"GSM993404": {"TREATMENT": "TNF (10ng/mL)+IL-17 (200ng/mL)", "TIME": "24 hour cytokine treatment"}}, {"GSM993403": {"TREATMENT": "TNF (10ng/mL)+IL-17 (20ng/mL)", "TIME": "24 hour cytokine treatment"}}, {"GSM993402": {"TREATMENT": "IL-17 (200ng/mL)", "TIME": "24 hour cytokine treatment"}}, {"GSM99340": {"TREATMENT": "IL-17 (20ng/mL)", "TIME": "24 hour cytokine treatment"}}, {"GSM993400": {"TREATMENT": "TNF (10ng/mL)", "TIME": "24 hour cytokine treatment"}}, {"GSM993399": {"TREATMENT": "Ctrl", "TIME": "24 hour cytokine treatment"}}], "id": 2397, "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "In this study, we sought to determine how IL-17 and TNF influence normal human melanocytes,  either alone, or with both cytokines...", "geo_gse_id": "E-GEOD-40413", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 12, "tags": ["line", "melanocyte", "serum"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "il-17-and-tnf-synergistically-induce-growth-associ", "geo_id_plat": "E-GEOD-40413_A-AFFY-44", "name": "IL-17 and TNF synergistically induce growth-associated cytokines in melanocytes while suppressing melanogenesis", "created": "Jul.12, 2014", "summary": "In this study, we sought to determine how IL-17 and TNF influence normal human melanocytes,  either alone, or with both cytokines together. We reveal a dichotomous effect of IL-17 and TNF, which not only elicit essential mitogenic cytokines but also suppress melanogenesis by down-regulating genes of melanogenesis pathway Comparison of one batch of primary human melanocyte line cultured in serum free media, treated with TNF and/or IL-17, for either 24 or 48 hours.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-40413", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-40413/samples/"}