{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSM99064": {"GENOTYPE": "Lsd1fl/fl"}}, {"GSM99064": {"GENOTYPE": "Lsd1fl/fl"}}, {"GSM99064": {"GENOTYPE": "Lsd1fl/fl"}}, {"GSM990644": {"GENOTYPE": "Lsd1fl/fl Mx1Cre"}}, {"GSM990644": {"GENOTYPE": "Lsd1fl/fl Mx1Cre"}}, {"GSM990644": {"GENOTYPE": "Lsd1fl/fl Mx1Cre"}}], "id": 6983, "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "We discovered that mice with hematopoietic-specific deletion of Lsd1 lacked Gr-1+ Mac1+ neutrophilic granulocytes whereas the numbers of...", "geo_gse_id": "E-GEOD-40282", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 6, "tags": ["bone", "bone marrow", "genome"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "gene-expression-data-of-lsd1flfl-and-lsd1flfl-mx1c", "geo_id_plat": "E-GEOD-40282_A-AFFY-45", "name": "Gene expression data of Lsd1fl/fl and Lsd1fl/fl Mx1Cre Gr1dim Mac1 granulocytic progenitor cells.", "created": "Nov.12, 2014", "summary": "We discovered that mice with hematopoietic-specific deletion of Lsd1 lacked Gr-1+ Mac1+ neutrophilic granulocytes whereas the numbers of Gr-1dim Mac1+ granulocytic progenitor cells was increased. To determine the genes altered by Lsd1-loss, Gr-1dim Mac1+ granulocytic progenitor cells from Lsd1fl/fl and Lsd1fl/fl Mx1Cre mice were FACS-purified to be analyzed by gene expression profiling. Primary Gr-1dim Mac1+ granulocytic progenitor cells were isolated from the bone marrow of Lsd1fl/fl and Lsd1fl/fl Mx1Cre animals by FACS-sorting, one week after the final p(I:C) dose. Total RNA from three biological replicates per genotype was extracted and used to hybridize to Affymetrix expression arrays using the Mouse Genome 430 2.0 array platform.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-40282", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-40282/samples/"}