ArrayExpress Uploader02633transfected with wild-type APC-expressing vector, transfected with Control siRNAtransfected with wild-type APC-expressing vector, transfected with Control siRNAtransfected with wild-type APC-expressing vector, transfected with Control siRNAtransfected with wild-type APC-expressing vector, transfected with Control siRNAstably transfected with empty vector, transfected with beta-catenin siRNAstably transfected with empty vector, transfected with beta-catenin siRNAstably transfected with empty vector, transfected with beta-catenin siRNAstably transfected with empty vector, transfected with beta-catenin siRNAstably transfected with empty vector, transfected with TAZ siRNAstably transfected with empty vector, transfected with TAZ siRNAstably transfected with empty vector, transfected with TAZ siRNAstably transfected with empty vector, transfected with TAZ siRNAstably transfected with empty vector, transfected with Control siRNAstably transfected with empty vector, transfected with Control siRNAstably transfected with empty vector, transfected with Control siRNAstably transfected with empty vector, transfected with Control siRNAarrayexpress_sid4To investigate the role of TAZ downstream of the abberrant Wnt signaling in CRC cells, we compared the expression profiles of parental...23245942E-GEOD-39904/profile/8773/arrayexpressuploader116leftDec.12, 2014Falserole-of-taz-as-mediator-of-wnt-signaling-sw480E-GEOD-39904_A-AFFY-44Role of TAZ as mediator of Wnt signaling (SW480)Jul.12, 2014To investigate the role of TAZ downstream of the abberrant Wnt signaling in CRC cells, we compared the expression profiles of parental SW480 cells (empty vector) transfected with siControl, siTAZ, sibeta-catenin or reconstituted with wild type APC and transfected with siControl Keywords: expression profiling by array We collected RNA from parental SW480 cells (empty vector) transfected with siControl, siTAZ, sibeta-catenin or from SW480 cells reconstituted with wild type APC and transfected with siControl. Cells were left untreated in normal culturing conditions before harvesting. Samples were then processed for total RNA extraction and hybridization on Affymetrix microarrays. Four biological replicas (A, B, C, D) were used for each of the 4 conditions (1: siControl, control cells; 2: siTAZ cells; 3: sibeta-catenin (sibcat) cells; 4.APC reconstituted cells) for a total of 16 samples.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-39904humanhttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-39904/samples/