Dataset: Expression profiling of human prostate VCaP and LNCaP cancer cells after silencing ERG or ETV1, respectively
Chromosomal rearrangements involving ETS factors, ERG and ETV1, occur frequently in prostate cancer. We here examine human prostate...
Chromosomal rearrangements involving ETS factors, ERG and ETV1, occur frequently in prostate cancer. We here examine human prostate cancer cells control VCaP and LNCaP cells with ERG- or ETV1-silenced VCaP or LNCaP cells, respectively, in hormone deprived and stimulated conditions. VCAP and LNCaP cells, 24 hr after ERG or ETV1 RNA interference, respectively, were grown in hormone-depleted conditions for 2 days, and then in the presence of EtOH (vehicle) or 10nM DHT for 16hr. Total RNA was extracted from three biological replicates. This was used to hybridize to Affymetrix expression arrays using the HG-U133 Plus 2.0 platform.
- Species:
- human
- Samples:
- 24
- Source:
- E-GEOD-39354
- Updated:
- Dec.12, 2014
- Registered:
- Jul.12, 2014
Factors:
(via ArrayExpress)
| Sample | CELL LINE | TREATMENT |
|---|---|---|
| GSM966545 | LNCAP | transfected with shETV1 were grown in androgen deprived serum for 2 days and then in the presence of 10nM DHT |
| GSM966545 | LNCAP | transfected with shETV1 were grown in androgen deprived serum for 2 days and then in the presence of 10nM DHT |
| GSM966545 | LNCAP | transfected with shETV1 were grown in androgen deprived serum for 2 days and then in the presence of 10nM DHT |
| GSM966542 | LNCAP | transfected with siControl were grown in androgen deprived serum for 2 days and then in the presence of 10nM DHT |
| GSM966542 | LNCAP | transfected with siControl were grown in androgen deprived serum for 2 days and then in the presence of 10nM DHT |
| GSM966542 | LNCAP | transfected with siControl were grown in androgen deprived serum for 2 days and then in the presence of 10nM DHT |
| GSM966539 | LNCAP | transfected with shETV1 were grown in androgen deprived serum for 2 days and then in the presence of EtOH |
| GSM966539 | LNCAP | transfected with shETV1 were grown in androgen deprived serum for 2 days and then in the presence of EtOH |
| GSM966539 | LNCAP | transfected with shETV1 were grown in androgen deprived serum for 2 days and then in the presence of EtOH |
| GSM966536 | LNCAP | transfected with siControl were grown in androgen deprived serum for 2 days and then in the presence of EtOH |
| GSM966536 | LNCAP | transfected with siControl were grown in androgen deprived serum for 2 days and then in the presence of EtOH |
| GSM966536 | LNCAP | transfected with siControl were grown in androgen deprived serum for 2 days and then in the presence of EtOH |
| GSM966533 | VCaP | transfected with siERG were grown in androgen deprived serum for 2 days and then in the presence of 10nM DHT |
| GSM966533 | VCaP | transfected with siERG were grown in androgen deprived serum for 2 days and then in the presence of 10nM DHT |
| GSM966533 | VCaP | transfected with siERG were grown in androgen deprived serum for 2 days and then in the presence of 10nM DHT |
| GSM966530 | VCaP | transfected with siControl were grown in androgen deprived serum for 2 days and then in the presence of 10nM DHT |
| GSM966530 | VCaP | transfected with siControl were grown in androgen deprived serum for 2 days and then in the presence of 10nM DHT |
| GSM966530 | VCaP | transfected with siControl were grown in androgen deprived serum for 2 days and then in the presence of 10nM DHT |
| GSM966527 | VCaP | transfected with siERG were grown in androgen deprived serum for 2 days and then in the presence of EtOH |
| GSM966527 | VCaP | transfected with siERG were grown in androgen deprived serum for 2 days and then in the presence of EtOH |
| GSM966527 | VCaP | transfected with siERG were grown in androgen deprived serum for 2 days and then in the presence of EtOH |
| GSM966524 | VCaP | transfected with siControl were grown in androgen deprived serum for 2 days and then in the presence of EtOH |
| GSM966524 | VCaP | transfected with siControl were grown in androgen deprived serum for 2 days and then in the presence of EtOH |
| GSM966524 | VCaP | transfected with siControl were grown in androgen deprived serum for 2 days and then in the presence of EtOH |