{"platform": 6, "owner": "ArrayExpress Uploader", "ownerprofile_id": "arrayexpress_sid", "species": "mouse", "factors": [{"GSM950616": {"GENOTYPE": "wildtype", "ORGANISM PART": "subiculum and retrosplenial cortex"}}, {"GSM950616": {"GENOTYPE": "wildtype", "ORGANISM PART": "subiculum and retrosplenial cortex"}}, {"GSM950616": {"GENOTYPE": "wildtype", "ORGANISM PART": "subiculum and retrosplenial cortex"}}, {"GSM950619": {"GENOTYPE": "D6/Zbtb20S transgenic", "ORGANISM PART": "CA1-transformed subiculum and retrosplenial cortex"}}, {"GSM950619": {"GENOTYPE": "D6/Zbtb20S transgenic", "ORGANISM PART": "CA1-transformed subiculum and retrosplenial cortex"}}, {"GSM950619": {"GENOTYPE": "D6/Zbtb20S transgenic", "ORGANISM PART": "CA1-transformed subiculum and retrosplenial cortex"}}], "id": 6933, "pop_total": 0, "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-38837", "summary_wrapped": "The transcriptional repressor Zbtb20 is essential for specification of hippocampal CA1 pyramidal neurons. Moreover, ectopic expression of...", "pubmed_id": 23283686, "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 2, "sample_count": 6, "tags": ["cortex", "lipid", "subiculum"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "zbtb20-mediated-repression-of-genes-in-developing", "geo_id_plat": "E-GEOD-38837_A-AFFY-45", "name": "Zbtb20-mediated repression of genes in developing CA1 pyramidal neurons", "created": "Nov.12, 2014", "summary": "The transcriptional repressor Zbtb20 is essential for specification of hippocampal CA1 pyramidal neurons. Moreover, ectopic expression of Zbtb20 is sufficient to transform subicular and retrosplenial areas of D6/Zbtb20S mice to CA1. We used microarrays to identify genes that are repressed by Zbtb20 in developing CA1 pyramidal neurons in the CA1-transformed cortex of D6/Zbtb20S mice. For RNA extraction and hybridization on Affymetrix microarrays, we isolated the CA1-transformed subiculum and retrosplenial cortex from postnatal day 1 D6/Zbtb20S mice, as well as corresponding areas from their wildtype littermates. Total RNA was extracted using the RNeasy Lipid Tissue Mini Kit (Qiagen). Each RNA sample represents a pool of RNA obtained from dissected tissues of seven animals.", "geo_gse_id": "E-GEOD-38837", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-38837/samples/"}