ArrayExpress Uploader0humanLeft-sided colitis46not specifiedazathioprinefemalePancolitis512azathioprinemalePancolitis624azathioprinefemalePancolitis3414azathioprinefemalePancolitis41155-ASAfemalePancolitis303Systemic steroidsfemaleLeft-sided colitis36not specifiedNo treatmentfemaleLeft-sided colitis5810No treatmentmalePancolitis437azathioprinefemalePancolitis437azathioprinefemalePancolitis34135-ASAfemalePancolitis34135-ASAfemaleLeft-sided colitis471azathioprinefemaleLeft-sided colitis471azathioprinefemaleLeft-sided colitis4175-ASAfemaleLeft-sided colitis4175-ASAfemaleLeft-sided colitis393azathioprinemaleLeft-sided colitis393azathioprinemaleLeft-sided colitis347azathioprinemaleLeft-sided colitis347azathioprinemaleLeft-sided colitis40135-ASAfemaleLeft-sided colitis40135-ASAfemalePancolitis60295-ASAfemaleLeft-sided colitis363azathioprinefemaleLeft-sided colitis3385-ASAmaleLeft-sided colitis63105-ASAfemaleLeft-sided colitis5385-ASAmaleLeft-sided colitis60225-ASAfemalePancolitis506azathioprinemaleLeft-sided colitis4013azathioprinefemale--50----female--40----male--50----male--38----female--22----female--54----female--36----female--55----female--60----female--45----female--41----male--30----male--20----male2690arrayexpress_sid4Ulcerative colitis (UC) is a chronic inflammatory disease of the colon with preiods of active disease followed by remission. We performed...23135761E-GEOD-38713/profile/8773/arrayexpressuploader543colitiscolondiseasegenomemucosaulcerative colitisDec.12, 2014FalseE-GEOD-38713_A-AFFY-44expression-data-from-intestinal-mucosa-of-patientsExpression data from intestinal mucosa of patients with UCJul.12, 2014Ulcerative colitis (UC) is a chronic inflammatory disease of the colon with preiods of active disease followed by remission. We performed a whole-genome transcriptional analysis of colonic biopsies from patients with histologically active and inactive UC, as well as non-inflammatory controls. Ulcerative colitis patients and non-inflammatory controls were collected for RNA extraction and hybridization on Affymetrix microarrays. Inclusion criteria for UC patients were: age between 18 and 65, diagnosis of UC established at least 6 months before inclusion and exclusion of concomitant infection. Active disease was defined by endoscopic and histologic score: Mayo sub score >=2 and MATTS >=3 respectively . Inactive disease was also defined by endoscopic and histologic score: Mayo sub score =0 and MATTS <=2 respectively, and a remission state for a minimum of 5 month prior to biopsy collection, and remained inactive for at least 6 months after. Uninvolved mucosa from patients with active UC was defined as a colonic segment with completely normal endoscopic appearance, normal histology, and absence of any previous evidence of active disease. Finally, a total of 43 biopsies were analyzed: 13 healthy controls, 8 inactive UC, 7 non-involved active UC and 15 involved active UC.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-38713http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-38713/samples/