ArrayExpress Uploader0mouseregular weightcontrolregular weightcontrolregular weightcontrolregular weightcontrolregular weightcontrolregular weightcontrolregular weightcontrolregular weightcontrolregular weightLPSregular weightLPSregular weightLPSregular weightLPSregular weightLPSregular weightLPSregular weightLPSregular weightLPSObesecontrolObesecontrolObesecontrolObesecontrolObesecontrolObesecontrolObesecontrolObesecontrolObeseLPSObeseLPSObeseLPSObeseLPSObeseLPSObeseLPSObeseLPSObeseLPS8626arrayexpress_sid8To identify key biological pathways that define susceptibility factors for pulmonary infection during obesity, diet-induced obese (DIO)...E-GEOD-38092/profile/8773/arrayexpressuploader232lipopolysaccharidelungnoseobesityDec.12, 2014Falsediet-induced-obesity-reprograms-the-inflammatory-rE-GEOD-38092_A-AFFY-36Diet-Induced Obesity Reprograms the Inflammatory Response of the Murine Lung to Inhaled EndotoxinNov.24, 2014To identify key biological pathways that define susceptibility factors for pulmonary infection during obesity, diet-induced obese (DIO) and regular weight (RW) C57BL/6 mice were exposed to 0.5 µg/L inhaled lipopolysaccharide (LPS) for 1 hr/d for 4 days over a period of 2 weeks. Transcriptional responses were measured by global microarray analysis of lung tissue. Groups (N=8 biological replicates) of regular weight (RW) and diet-induced obese (DIO) C57BL/6 mice (15-weeks old at start of exposures) were exposed to either filtered air (sham controls, SC) or 0.5 µg/L LPS by nose-only inhalation exposure for 1 hr/day for 4 days over a 10-day period with necropsies occurring on the day following the last exposure (Day 11).http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-38092http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-38092/samples/