{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "mouse", "factors": [{"GSM932887": {"GENOTYPE": "RAG-2-deficient"}}, {"GSM932887": {"GENOTYPE": "RAG-2-deficient"}}, {"GSM932887": {"GENOTYPE": "RAG-2-deficient"}}, {"GSM932890": {"GENOTYPE": "Artemis-deficient"}}, {"GSM932890": {"GENOTYPE": "Artemis-deficient"}}, {"GSM932890": {"GENOTYPE": "Artemis-deficient"}}], "id": 6887, "ownerprofile_id": "arrayexpress_sid", "platform": 6, "summary_wrapped": "The objective is to identify genes that are differentially expressed following the introduction of DNA double-strand breaks (DSBs) by the...", "geo_gse_id": "E-GEOD-38044", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 6, "tags": ["cell", "genome"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "gene-activation-by-rag-mediated-dna-double-strand", "geo_id_plat": "E-GEOD-38044_A-AFFY-45", "name": "Gene activation by Rag-mediated DNA double-strand breaks in G1-phase murine pre-B cells", "created": "Nov.12, 2014", "summary": "The objective is to identify genes that are differentially expressed following the introduction of DNA double-strand breaks (DSBs) by the Rag proteins in murine pre-B cells. Cells lacking Artemis are used since the Rag-induced DSBs will not be repaired, and thus, will provide a continuous stimulus to the cell. Murine v-abl-transformed pre-B cells were treated with 3 uM STI571 for 48 hours. Cell types included RAG-2-deficient (3 biological replicates) and Artemis-deficient (3 biological replicates) G1-phase pre-B cells. Each sample was hybridized once using Affymetrix Mouse Genome 2.0 GeneChip arrays (Mouse 430 v2, Affymetrix, Santa Clara, CA). Data were analyzed using the RAG-2-deficient samples as the controls.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-38044", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-38044/samples/"}