ArrayExpress Uploader02524metastatic castration-resistant prostate cancer patientmetastatic castration-resistant prostate cancer patientmetastatic castration-resistant prostate cancer patienthealthy donorhealthy donorhealthy donorarrayexpress_sid4We analyzed the global gene expression pattern of Tregs between healthy donors and prostate cancer patients. We found that genes related...23319273E-GEOD-38043/profile/8773/arrayexpressuploader16cancercellperipheralprostateprostate cancerDec.12, 2014Falsedysregulated-expression-of-genes-in-regulatory-t-cE-GEOD-38043_A-AFFY-44Dysregulated expression of genes in regulatory T cells from metastatic castration-resistant prostate cancer patientsJul.12, 2014We analyzed the global gene expression pattern of Tregs between healthy donors and prostate cancer patients. We found that genes related to cell cycle, cellular proliferation, immune responses, hematological system development and function were differentially expressed in Tregs from prostate cancer patients. Total RNA samples of Tregs, isolated from peripheral blood, were obtained from three separate healthy donors and three metastatic castration-resistant prostate cancer patients. Global gene expression pattern was examined by performing GeneChip microarray hybridization. Genes differentially expressed between the two groups of donors were sorted and categorized based on their biological functions.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-38043humanhttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-38043/samples/