ArrayExpress Uploader04491healthy controlcontrolbrain white matterhealthy controlcontrolbrain white mattermultiple sclerosis early stage-active inflammationactive plaquemultiple sclerosis brain lesionmultiple sclerosis following demyelination-active inflammationchronice active plaquemultiple sclerosis brain lesionmultiple sclerosis following demyelination-active inflammationchronice active plaquemultiple sclerosis brain lesionmultiple sclerosis after inflammation has subsided-late stagechronic plaquemultiple sclerosis brain lesionmultiple sclerosis after inflammation has subsided-late stagechronic plaquemultiple sclerosis brain lesionarrayexpress_sid4Gene transcripts and proteins expressed during disease pathogenesis identify targets for therapy. We performed microarray analysis of...24475162E-GEOD-38010/profile/8773/arrayexpressuploader37braindiseasemultiple sclerosisDec.12, 2014Falsejanus-like-opposing-roles-of-cd47-in-autoimmune-brE-GEOD-38010_A-AFFY-44Janus-Like Opposing Roles of CD47 in Autoimmune Brain Inflammation in Human and MiceSep.19, 2014Gene transcripts and proteins expressed during disease pathogenesis identify targets for therapy. We performed microarray analysis of histologically characterized multiple sclerosis (MS) brain lesions in comparison with control brain samples to identify differentially expressed molecules. We identified CD47 as a target of interest and studied its biology in MS and EAE. We isolated total RNA from acute plaque (AP), chronic active plaque (CAP) and chronic plaque (CP) from MS brains and white matter from healthy controls and performed microarray studies.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-38010humanhttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-38010/samples/