{"owner": "ArrayExpress Uploader", "pop_total": 0, "id": 4491, "factors": [{"GSM931812": {"DISEASE STATE": "healthy control", "HISTOLOGY": "control", "ORGANISM PART": "brain white matter"}}, {"GSM931812": {"DISEASE STATE": "healthy control", "HISTOLOGY": "control", "ORGANISM PART": "brain white matter"}}, {"GSM931814": {"DISEASE STATE": "multiple sclerosis early stage-active inflammation", "HISTOLOGY": "active plaque", "ORGANISM PART": "multiple sclerosis brain lesion"}}, {"GSM931815": {"DISEASE STATE": "multiple sclerosis following demyelination-active inflammation", "HISTOLOGY": "chronice active plaque", "ORGANISM PART": "multiple sclerosis brain lesion"}}, {"GSM931815": {"DISEASE STATE": "multiple sclerosis following demyelination-active inflammation", "HISTOLOGY": "chronice active plaque", "ORGANISM PART": "multiple sclerosis brain lesion"}}, {"GSM931817": {"DISEASE STATE": "multiple sclerosis after inflammation has subsided-late stage", "HISTOLOGY": "chronic plaque", "ORGANISM PART": "multiple sclerosis brain lesion"}}, {"GSM931817": {"DISEASE STATE": "multiple sclerosis after inflammation has subsided-late stage", "HISTOLOGY": "chronic plaque", "ORGANISM PART": "multiple sclerosis brain lesion"}}], "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "Gene transcripts and proteins expressed during disease pathogenesis identify targets for therapy. We performed microarray analysis of...", "pubmed_id": 24475162, "geo_gse_id": "E-GEOD-38010", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 3, "sample_count": 7, "tags": ["brain", "disease", "multiple sclerosis"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "janus-like-opposing-roles-of-cd47-in-autoimmune-br", "geo_id_plat": "E-GEOD-38010_A-AFFY-44", "name": "Janus-Like Opposing Roles of CD47 in Autoimmune Brain Inflammation in Human and Mice", "created": "Sep.19, 2014", "summary": "Gene transcripts and proteins expressed during disease pathogenesis identify targets for therapy. We performed microarray analysis of histologically characterized multiple sclerosis (MS) brain lesions in comparison with control brain samples to identify differentially expressed molecules. We identified CD47 as a target of interest and studied its biology in MS and EAE. We isolated total RNA from acute plaque (AP), chronic active plaque (CAP) and chronic plaque (CP) from MS brains and white matter from healthy controls and performed microarray studies.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-38010", "species": "human", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-38010/samples/"}