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<biogps><data><item key="owner">ArrayExpress Uploader</item><item key="pop_total">0</item><item key="id">2665</item><item key="factors"><item><item key="GSM929693"><item key="CELL LINE">CL1-5 lung cancer cell line</item><item key="VARIATION">expressing AK4 shRNA vector</item></item></item><item><item key="GSM929692"><item key="CELL LINE">CL1-5 lung cancer cell line</item><item key="VARIATION">expressing non-silencing shRNA vector</item></item></item><item><item key="GSM92969"><item key="CELL LINE">CL1-0 lung cancer cell line</item><item key="VARIATION">expressing AK4 vector</item></item></item><item><item key="GSM929690"><item key="CELL LINE">CL1-0 lung cancer cell line</item><item key="VARIATION">expressing control vector</item></item></item></item><item key="ownerprofile_id">arrayexpress_sid</item><item key="platform">4</item><item key="summary_wrapped">We demonstrate that AK4 down-regulation shRNAs significantly reduced cell migration and invasion in highly invasive lung cancer cell...</item><item key="pubmed_id">23002211</item><item key="geo_gse_id">E-GEOD-37903</item><item key="owner_profile">/profile/8773/arrayexpressuploader</item><item key="factor_count">2</item><item key="sample_count">4</item><item key="tags"><item>adenocarcinoma</item><item>cancer</item><item>cell</item><item>lung</item><item>lung adenocarcinoma</item><item>lung cancer</item></item><item key="lastmodified">Dec.12, 2014</item><item key="is_default">False</item><item key="geo_gds_id"/><item key="slug">expression-data-from-ak4-overexpression-in-cl1-0-l</item><item key="geo_id_plat">E-GEOD-37903_A-AFFY-44</item><item key="name">Expression data from AK4 overexpression in CL1-0 lung cancer cell line and AK4 knockdown in CL1-5 lung cancer cell line</item><item key="created">Jul.12, 2014</item><item key="summary">We demonstrate that AK4 down-regulation shRNAs significantly reduced cell migration and invasion in highly invasive lung cancer cell lines in vitro, as well as in lung metastases in vivo We used microarrays to analyze the AK4 regulated gene expression underlying invasion-metastasis cascade. CL1-0 lung adenocarcinoma cells with AK4 overexpression and CL1-5 cells with AK4 knockdown were selected for RNA extraction and hybridization on Affymetrix microarrays.</item><item key="source">http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-37903</item><item key="species">human</item><item key="sample_source">http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-37903/samples/</item></data></biogps>
