{"platform": 6, "owner": "ArrayExpress Uploader", "ownerprofile_id": "arrayexpress_sid", "species": "mouse", "factors": [{"GSM929067": {"TREATMENT": "none"}}, {"GSM929068": {"TREATMENT": "B-DNA (10ug/ml) for 4 hr"}}, {"GSM929069": {"TREATMENT": "CpG-B(3uM) for 4 hr"}}], "id": 6878, "pop_total": 0, "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-37854", "summary_wrapped": "Toll-like receptor and RIG-I-like receptor classs may evoke or instruct a distinct type of response that is more reflective of the...", "pubmed_id": 22610141, "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 1, "sample_count": 3, "tags": [], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "gene-expression-profile-in-peritoneal-macrophage-s", "geo_id_plat": "E-GEOD-37854_A-AFFY-45", "name": "Gene expression profile in peritoneal macrophage stimulated with B-DNA or CpG-B", "created": "Nov.12, 2014", "summary": "Toll-like receptor and RIG-I-like receptor classs may evoke or instruct a distinct type of response that is more reflective of the pathogen encountered.  Although this issue may be critical to a better understanding of the regulation of immune responses to microbial infections, it has not been addressed through a direct, side-by-side comparison of the two receptor classes. To address this, we performed microarray analysis of mRNAs from peritoneal macrophages stimulated with a synthetic B-form DNA, poly(dA-dT)\u30fbpoly(dT-dA) ( B-DNA) or a CpG-B oligonucleotide, which respectively activates RLRs or TLR9, and identified B-DNA inducible genes and CpG-B inducible genes. Peritoneal macrophages from B6 mice were stimulated with B-DNA (10\u03bcg/ml) or CpG-B(3\u03bcM) for 4 hous, and then subjected to microarray analysis.", "geo_gse_id": "E-GEOD-37854", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-37854/samples/"}