ArrayExpress Uploaderarrayexpress_sidhumansiRNA-TbetsiRNAc447504T-bet is pivotal for initiation and perpetuation of Th1 immunity. Identification of novel T-bet regulated genes is crucial for further...23095752E-GEOD-37595/profile/8773/arrayexpressuploader12genomeDec.12, 2014Falset-bet-regulated-genes-in-kg1-cellsE-GEOD-37595_A-AFFY-44T-bet regulated genes in KG1 cellsSep.19, 2014T-bet is pivotal for initiation and perpetuation of Th1 immunity. Identification of novel T-bet regulated genes is crucial for further understanding the biology of this transcription factor. By combining siRNA technology with genome-wide mRNA analysis, we sought to identify new T-bet regulated genes in IL-18-activated KG1 cells. KG1 cells were transfected with either control-siRNA (siRNAc) or siRNA targeting T-bet (siRNA-Tbet) and thereafter stimulated with IL-18. Total RNA was evaluated by genome-wide analysis using the Affymetrix GeneChip® Array System.http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-37595http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-37595/samples/