ArrayExpress Uploader0humanA673sh transiently with the pRS-sh-FOXO1 plasmid targeting endogenous FOXO1wt + doxycycline for 48h post transfectionA673sh transiently with the pRS-sh-FOXO1 plasmid targeting endogenous FOXO1wtA673sh transiently with the pRS-sh-scrambled plasmid + doxycycline for 48h post transfectionA673sh transiently with the pRS-sh-scrambled plasmidA673sh transiently with the pRS-sh-FOXO1 plasmid targeting endogenous FOXO1wt + doxycycline for 48h post transfectionA673sh transiently with the pRS-sh-FOXO1 plasmid targeting endogenous FOXO1wtA673sh transiently with the pRS-sh-scrambled plasmid + doxycycline for 48h post transfectionA673sh transiently with the pRS-sh-scrambled plasmidA673sh transiently with the pCDNA3-based FLAG-FOXO1-S249A/S298A plasmidA673sh transiently with the pCDNA3-based FLAG-FOXO1-AAA plasmidwith the empty vector control (pCDNA3)2373arrayexpress_sid4Transient transfection of a Ewing's Sarcoma cell line expressing type I EWS-FLI1 fusion and doxycycline-inducible short hairpin RNA...E-GEOD-37409/profile/8773/arrayexpressuploader111celllinesarcomaDec.12, 2014Falsere-activation-of-ews-fli1-suppressed-foxo1-expressE-GEOD-37409_A-AFFY-44Re-activation of EWS-FLI1 suppressed FOXO1 expression as a novel therapeutic strategy for Ewing´s sarcomaJul.12, 2014Transient transfection of a Ewing's Sarcoma cell line expressing type I EWS-FLI1 fusion and doxycycline-inducible short hairpin RNA against EWS-FLI1 (A673sh) In total, 7 samples were analysed: empty vector control and two nuclear directed AKT- and CDK2- phosphorylation resistant FOXO1 versions as well as sh-scrambled and sh-FOXO1, either in the presence (w.o. Doxy.) or absence of EWS-FLI1 (+ Doxy.) each 2 replicateshttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-37409http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-37409/samples/