Dataset: Gene expression profiling of ovaries collected from wild type (WT) mice and progesterone receptor (PR) knock out mice

Previous studies have shown that PR is a critical regulator of ovulation. The PR-null mice (PRKO) failed to ovulate due to a failure in the rupture of the preovulatory follicles. To experimentally induce ovulation, the wild type and PR null mice (C57BL/6, 24–28 d old) were injected ip with 5 IU of PMSG and 48 h later by 5 IU of hCG. Ovaries were collected at 11 h and total RNA was analyzed using Affymetrix mouse arrays

Species:

mouse

Samples:

2

Source:

E-GEOD-37354

PubMed:

23012316

Updated:

Dec.12, 2014

Registered:

Nov.12, 2014