ArrayExpress Uploaderarrayexpress_sidmousewild type genotypewild type genotypewild type genotypeTimp3-/-Timp3-/-Timp3-/-680406Activation of A Disintegrin and A Metalloprotease Domain17 (ADAM17) is involved in nephropathy, but the role of this metalloprotease and...E-GEOD-36336/profile/8773/arrayexpressuploader16diseasekidneykidney diseaseDec.12, 2014Falsetranscription-profiling-by-array-of-kidneys-from-dE-GEOD-36336_A-AFFY-45Transcription profiling by array of kidneys from diabetic wild type and T3-/- miceNov.12, 2014Activation of A Disintegrin and A Metalloprotease Domain17 (ADAM17) is involved in nephropathy, but the role of this metalloprotease and its inhibitor TIMP3 in diabetic kidney disease is unclear. We used microarray profiling to find genes differentially expressed in the 2 genotypes which could explain the more severe diabetic kidney disease features observed in T3-/- mice compared to the WT littermates. Total RNA was extracted from 3 WT and 3 Timp3-/- diabetic kidneyshttp://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-36336http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-36336/samples/