{"owner": "ArrayExpress Uploader", "pop_total": 0, "species": "human", "factors": [{"GSM878095": {"SAMPLE ID": "donor 1 (MSC population #276)", "GENDER": "female", "AGE": "42 yrs (middle-aged)", "PASSAGE": "passage 1"}}, {"GSM878096": {"SAMPLE ID": "donor 2 (MSC population #353)", "GENDER": "female", "AGE": "67 yrs (middle-aged)", "PASSAGE": "passage 2"}}, {"GSM878097": {"SAMPLE ID": "donor 3 (MSC population #295)", "GENDER": "male", "AGE": "61 yrs (middle-aged)", "PASSAGE": "passage 1"}}, {"GSM878098": {"SAMPLE ID": "donor 4 (MSC population #296)", "GENDER": "female", "AGE": "62 yrs (middle-aged)", "PASSAGE": "passage 1"}}, {"GSM878099": {"SAMPLE ID": "donor 5 (MSC population #247)", "GENDER": "female", "AGE": "56 yrs (middle-aged)", "PASSAGE": "passage 1"}}, {"GSM878109": {"SAMPLE ID": "donor 1 (MSC population #276)", "GENDER": "female", "AGE": "42 yrs", "PASSAGE": "long term-cultivation (cellular senescence state)"}}, {"GSM878110": {"SAMPLE ID": "donor 2 (MSC population #278)", "GENDER": "female", "AGE": "59 yrs", "PASSAGE": "long term-cultivation (cellular senescence state)"}}, {"GSM878": {"SAMPLE ID": "donor 3 (MSC population #271)", "GENDER": "female", "AGE": "64 yrs", "PASSAGE": "long term-cultivation (cellular senescence state)"}}, {"GSM878112": {"SAMPLE ID": "donor 4 (MSC population #277)", "GENDER": "male", "AGE": "54 yrs", "PASSAGE": "long term-cultivation (cellular senescence state)"}}, {"GSM878113": {"SAMPLE ID": "donor 5 (MSC population #274)", "GENDER": "male", "AGE": "63 yrs", "PASSAGE": "long term-cultivation (cellular senescence state)"}}], "id": 4425, "ownerprofile_id": "arrayexpress_sid", "platform": 4, "summary_wrapped": "In the present study we analyzed the effect of cellular senescence on the transcriptome of human mesenchymal stem cells (hMSC;...", "geo_gse_id": "E-GEOD-35957", "owner_profile": "/profile/8773/arrayexpressuploader", "factor_count": 4, "sample_count": 10, "tags": ["bone", "bone marrow", "hip", "osteoarthritis"], "lastmodified": "Dec.12, 2014", "is_default": false, "geo_gds_id": "", "slug": "effects-of-cellular-senescence-on-human-mesenchyma", "geo_id_plat": "E-GEOD-35957_A-AFFY-44", "name": "Effects of Cellular Senescence on Human Mesenchymal Stem Cells", "created": "Sep.19, 2014", "summary": "In the present study we analyzed the effect of cellular senescence on the transcriptome of human mesenchymal stem cells (hMSC; alternatively named mesenchymal stromal cells) from bone marrow. Human MSC were isolated from femoral heads of non-osteoporotic donors after total hip arthroplasty. Cells were isolated from human bone marrow according to the previously described protocol (Noth et al., 2002, J Orthop Res, 20/5, 1060-1069) under agreement of the local Ethics Committee of the University of W\u00fcrzburg. Bone marrow was obtained of femoral heads after total hip arthroplasty due to osteoarthritis and/or hip dysplasia. MSC were replated after reaching 70-90% confluence until they entered state of cellular senescence.  RNA samples of control cells were taken from passage 1 or passage 2.", "source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-35957", "sample_source": "http://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-35957/samples/"}